Children unlikely to get disproportionately hit by any future third wave of COVID19: AIIMS-WHO Study
New Delhi, Jun 17: The SARS-CoV-2 sero-positivity rate among children is high and comparable to the adult population and hence, it is unlikely that any future third wave of the prevailing COVID-19 variant would disproportionately affect children aged two years and above, according to the interim findings of an ongoing study conducted in the country.
The interim findings that have appeared on medRxiv, a pre-print server, are based on a mid-term analysis of the data of the 4,509 participants -- 700 children in the 2-17 years age group and 3,809 aged 18 years and above -- from five states.
The data collection period was from March 15 to June 10 from five sites -- Delhi Urban Resettlement Colony, Delhi Rural (villages in Faridabad district of Haryana under Delhi-NCR), Bhubaneswar Rural, Gorakhpur rural and Agartala rural.
The findings are part of an ongoing multi-centric, population-based, age-stratified prospective COVID-19 sero-prevalence study under WHO (World Health Organization) Unity studies conducted by experts, including doctors from the AIIMS -- Director Randeep Guleria and Professors from the Department of Centre for Community Medicine Puneet Misra, Shashi Kant and Sanjay K Rai -- in the five selected states with a proposed total sample size of 10,000.
"The seroprevalence was 55.7 per cent in the below 18 years age group and 63.5 per cent in the above 18 years age group. There was no statistically significant difference in prevalence between adult and children," the findings stated.
The site-wise numbers of available data among the 2-17 age group were 92, 189, 165, 146 and 108 for Delhi Urban Resettlement Colony, Delhi Rural, Bhubaneswar Rural, Gorakhpur Rural and Agartala Rural respectively.
The total serum antibody against the SARS-CoV-2 virus was assessed qualitatively by using a standard ELISA kit.
The study findings come amid concerns raised in the country regarding a probable third wave of COVID-19 where children and youngsters are likely to get affected the most.
Irrespective of the age group, rural sites had a lower sero-positivity rate compared to the urban site (in Delhi). Within the rural sites, children had a slightly lower sero-positivity rate compared to adults. However, this differential prevalence was not observed in the urban site, according to the findings.
"There was a slightly higher sero-positivity rate observed among female children. This finding was in contrast to the meta-analysis where it was shown that the prevalence is higher in men. This may be a chance finding due to small number of data available at the time of mid-term analysis," the study stated.
The higher seropositivity rate in children aged 10-17 years may be reflective of their higher mobility and independence compared to the younger children.
As reported in the literature, a large proportion of children (50.9 per cent) had asymptomatic COVID-19 infection.
In India, the sero-prevalence among children and youngsters was estimated as a part of a larger nationwide survey on adults. The second nationwide sero-prevalence study done in August-September 2020 had reported a nine per cent seropositivity among 3,021 children aged 10-17 years while according to this study, it is 60.3 per cent.
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SIT formed to probe second sexual assault case against expelled Cong MLA Mamkootathil
Thiruvananthapuram (PTI): A Special Investigation Team (SIT) has been constituted to probe a second case of sexual assault against expelled Congress MLA Rahul Mamkootathil, police officials said on Friday.
The SIT will be led by G Poonguzhali, Assistant Inspector General at the Police Headquarters.
The team also includes a DSP rank officer and sub-inspectors, officials added.
The second sexual assault complaint was received by the Kerala Pradesh Congress Committee, which it forwarded to the state police chief.
ALSO READ: Cong expels rape-accused MLA Mamkootathil from party's primary membership
Following this, the Crime Branch registered a case and launched an investigation.
Crime Branch officials said the email complaint contained only the sender's email ID and no other contact details.
As part of the probe, they have sent a reply email requesting that the complainant contact them and provide her statement.
The complainant has alleged that she was sexually assaulted under the false promise of marriage, a Crime Branch official said.
However, details such as the location and date of the alleged incident are not currently available to the police.
The SIT will attempt to trace the sender of the email and record her statement, which is crucial for further investigation, the officer said.
Mamkootathil was expelled from the Congress party on Thursday after a court here rejected his anticipatory bail petition in another rape case.
Police said he is currently absconding, and a manhunt is underway in Kerala and neighbouring states.
