London, June 13: A high blood pressure level but still below the usual threshold for treating hypertension can put 50-year-olds at increased risk of developing dementia later, revealed a study led by an Indian-origin researcher.
According to the American Heart Association, normal blood pressure is below 120/80 mmHg.
People with a systolic blood pressure (the top number) of 130 mmHg or more at the age of 50 had a 45 per cent greater risk of developing dementia than those with a lower level at the same age.
The risk was 47 per cent even in people with no heart or blood vessel-related conditions.
"Our work confirms the detrimental effects of midlife hypertension for risk of dementia," said lead author Archana Singh-Manoux, Professor at the French National Institute of Health and Medical Research (INSERM) in Paris.
The reason for the increased risk of dementia includes the fact that high blood pressure is linked to silent or mini strokes (where symptoms often are not noticeable), damage to the white matter in the brain, which contains many of the brain's nerve fibres, and restricted blood supply to the brain.
This damage may underlie the resulting decline in the brain's processes, the researchers explained in the study of nearly 9,000 people, published in the European Heart Journal.
However, the association was not seen at the ages of 60 and 70, and diastolic blood pressure (the bottom number) was not linked to dementia.
"Our analysis suggests that the importance of mid-life hypertension on brain health is due to the duration of exposure," the researcher said.
"So we see an increased risk for people with raised blood pressure at age 50, but not 60 or 70, because those with hypertension at age 50 are likely to be 'exposed' to this risk for longer," she added.
Another study reported in the journal Cardiovascular Research showed that higher risk of developing dementia in hypertensive patients occurs due to significant alterations in three specific white matter fibre-tracts linked to executive functions, processing speed, memory and related learning tasks -- brain areas associated with dementia.
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Chandigarh (PTI): Punjab Chief Minister Bhagwant Mann strongly condemned the attack on Shiromani Akali Dal leader Sukhbir Singh Badal, who was fired at while performing 'sewa' outside the Golden Temple on Wednesday morning, and directed police to investigate the incident.
The chief minister also lauded the promptness of the Punjab Police in nabbing the attacker.
The man missed Badal as he was overpowered by police. The audacious attack was captured on cameras of media persons who had gathered outside the Sikh shrine to cover the second day of Badal's penance for "mistakes" committed by the SAD government in Punjab from 2007 to 2017.
"Punjab Police prevented a major incident from happening today. It is the result of the promptness of the Punjab Police that the conspiracy to defame Punjab and Punjabis has failed," Mann said in a post on X.
"The police achieved great success by arresting the assailant on the spot with their promptness... I strongly condemn the attack on Sukhbir Badal ji. I have issued strict instructions to the police to immediately investigate the incident and submit a report," he added.
Police identified the shooter as Narain Singh Chaura, a resident of Dera Baba Nanak. After the attack, he was whisked away by security officials.
Television footage showed the shooter slowly walking towards Badal, who was sitting in a wheelchair due to a fractured leg, and pulling out a gun from his pocket. A police official in plainclothes standing near Badal quickly intervened and grabbed the attacker's hands. In the melee, a bullet hit the wall behind Badal, who escaped unhurt.