How middle-age hypertension raises dementia risk later
London, June 13: A high blood pressure level but still below the usual threshold for treating hypertension can put 50-year-olds at increased risk of developing dementia later, revealed a study led by an Indian-origin researcher.
According to the American Heart Association, normal blood pressure is below 120/80 mmHg.
People with a systolic blood pressure (the top number) of 130 mmHg or more at the age of 50 had a 45 per cent greater risk of developing dementia than those with a lower level at the same age.
The risk was 47 per cent even in people with no heart or blood vessel-related conditions.
"Our work confirms the detrimental effects of midlife hypertension for risk of dementia," said lead author Archana Singh-Manoux, Professor at the French National Institute of Health and Medical Research (INSERM) in Paris.
The reason for the increased risk of dementia includes the fact that high blood pressure is linked to silent or mini strokes (where symptoms often are not noticeable), damage to the white matter in the brain, which contains many of the brain's nerve fibres, and restricted blood supply to the brain.
This damage may underlie the resulting decline in the brain's processes, the researchers explained in the study of nearly 9,000 people, published in the European Heart Journal.
However, the association was not seen at the ages of 60 and 70, and diastolic blood pressure (the bottom number) was not linked to dementia.
"Our analysis suggests that the importance of mid-life hypertension on brain health is due to the duration of exposure," the researcher said.
"So we see an increased risk for people with raised blood pressure at age 50, but not 60 or 70, because those with hypertension at age 50 are likely to be 'exposed' to this risk for longer," she added.
Another study reported in the journal Cardiovascular Research showed that higher risk of developing dementia in hypertensive patients occurs due to significant alterations in three specific white matter fibre-tracts linked to executive functions, processing speed, memory and related learning tasks -- brain areas associated with dementia.
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Ex-bureaucrat Raj Kumar Goyal sworn in as CIC; eight new information commissioners take oath
New Delhi (PTI): After a gap of nine years, transparency watchdog Central Information Commission attained its full strength with the appointment of former IAS officer Raj Kumar Goyal and eight other information commissioners, who took the oath of office on Monday.
A three-member panel headed by Prime Minister Narendra Modi last week recommended their names for the appointment.
President Droupadi Murmu administered the oath of office to Goyal as the chief information commissioner (CIC) at a ceremony held at the Rashtrapati Bhavan, her office said in a communique.
The event was attended by Vice President C P Radhakrishnan and Union Minister of State for Personnel Jitendra Singh, among others.
Goyal is a 1990-batch (retired) IAS officer of the Arunachal Pradesh-Goa-Mizoram-Union Territories (AGMUT) cadre. He superannuated as secretary, Department of Justice under the Ministry of Law and Justice, on August 31.
He has also served as secretary (border management) in the Home Ministry and held key posts both at the Centre and in the erstwhile state of Jammu and Kashmir.
The post of CIC fell vacant after Heeralal Samariya completed his term on September 13.
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The Commission is headed by a CIC and can have a maximum of 10 information commissioners. With the new appointments, the Commission attained its full strength after a gap of over nine years, according to transparency activists.
In the presence of two incumbent Information Commissioners, Anandi Ramalingam and Vinod Kumar Tiwari, Goyal administered the oath of office to eight new appointees at the swearing-in ceremony.
They included former Railway Board chief Jaya Verma Sinha, former IPS officer Swagat Das -- who held key posts in the Intelligence Bureau, Home Ministry and Cabinet Secretariat, among others -- Central Secretariat Service (CSS) officer Sanjeev Kumar Jindal, former IAS officer Surendra Singh Meena and ex-Indian Forest Service officer Khushwant Singh Sethi.
Senior journalists P R Ramesh and Ashutosh Chaturvedi, and former Indian Legal Service officer Sudha Rani Relangi, have also been sworn in as information commissioners.
Relangi has also worked as the director of prosecution, Central Bureau of Investigation and joint secretary and legislative counsel in the Ministry of Law and Justice.
The names of the CIC and eight information commissioners were cleared during the meeting of the Modi-led committee comprising Union Home Minister Amit Shah and Leader of Opposition in Lok Sabha Rahul Gandhi.
