New smart bandage may monitor, medicate chronic wounds
New York, July 7: Researchers have developed a prototype bandage designed to actively monitor the condition of chronic wounds and deliver appropriate drug treatments to improve the chances of healing.
While the lab-tested bandages remain to be assessed in a clinical context, a study, published in the journal Small, said the aim is to transform bandaging from a traditionally passive treatment into a more active paradigm to address a persistent and difficult medical challenge.
According to the researchers, chronic skin wounds from burns, diabetes and other medical conditions can overwhelm the regenerative capabilities of the skin and often lead to persistent infections and amputations.
"We have been able to take a new approach to bandages because of the emergence of flexible electronics," said co-author Sameer Sonkusale, Professor at Tufts University in the US.
The researchers designed the bandages with heating elements and thermoresponsive drug carriers that can deliver tailored treatments in response to embedded pH and temperature sensors that track infection and inflammation.
They said that pH of a chronic wound is one of the key parameters for monitoring its progress. Normal healing wounds fall within the range of pH 5.5 to 6.5, whereas non-healing infected wounds can have pH well above 6.5.
Temperature is also an important parameter, providing information on the level of inflammation in and around the wound, they added.
While the smart bandages in this study combine pH and temperature sensors, the team have also developed flexible sensors for oxygenation -- another marker of healing -- which can be integrated into the bandage.
Inflammation could also be tracked not just by heat, but by specific biomarkers as well, the researchers said.
A microprocessor reads the data from the sensors and can release drug on demand from its carriers by heating the gel.
The entire construct is attached to a transparent medical tape to form a flexible bandage less than 3 mm thick. Components were selected to keep the bandage cheap and disposable, except for the microprocessor, which can be re-used.
The researchers noted that smart bandages could provide real time monitoring and delivery of treatment with limited intervention from the patient or caregivers.
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Kenya cancels airport and energy deals with Adani group after US indicts the tycoon
Nairobi, Nov 21: Kenya's president said Thursday he has cancelled multimillion-dollar airport expansion and energy deals with Indian tycoon Gautam Adani after US bribery and fraud indictments against one of Asia's richest men.
President William Ruto in a state of the nation address said the decision was made “based on new information provided by our investigative agencies and partner nations.” He didn't specify the United States.
The Adani group had been in the process of signing an agreement that would modernize Kenya's main airport in the capital, Nairobi, with an additional runway and terminal constructed, in exchange for the group running the airport for 30 years.
The widely criticised deal had sparked anti-Adani protests in Kenya and a strike by airport workers, who said it would lead to degraded working conditions and job losses in some cases.
The Adani group had also been awarded a deal to construct power transmission lines in Kenya, East Africa's business hub.
Also Thursday, Energy Minister Opiyo Wandayi told a parliamentary committee there had been no bribery or corruption involved on Kenya's part in signing that deal.
US prosecutors indicted Adani this week on charges he duped investors in a massive solar energy project in India by concealing that it was facilitated by an alleged bribery scheme. He was charged with securities fraud and conspiracy to commit securities and wire fraud.
