New smart bandage may monitor, medicate chronic wounds
New York, July 7: Researchers have developed a prototype bandage designed to actively monitor the condition of chronic wounds and deliver appropriate drug treatments to improve the chances of healing.
While the lab-tested bandages remain to be assessed in a clinical context, a study, published in the journal Small, said the aim is to transform bandaging from a traditionally passive treatment into a more active paradigm to address a persistent and difficult medical challenge.
According to the researchers, chronic skin wounds from burns, diabetes and other medical conditions can overwhelm the regenerative capabilities of the skin and often lead to persistent infections and amputations.
"We have been able to take a new approach to bandages because of the emergence of flexible electronics," said co-author Sameer Sonkusale, Professor at Tufts University in the US.
The researchers designed the bandages with heating elements and thermoresponsive drug carriers that can deliver tailored treatments in response to embedded pH and temperature sensors that track infection and inflammation.
They said that pH of a chronic wound is one of the key parameters for monitoring its progress. Normal healing wounds fall within the range of pH 5.5 to 6.5, whereas non-healing infected wounds can have pH well above 6.5.
Temperature is also an important parameter, providing information on the level of inflammation in and around the wound, they added.
While the smart bandages in this study combine pH and temperature sensors, the team have also developed flexible sensors for oxygenation -- another marker of healing -- which can be integrated into the bandage.
Inflammation could also be tracked not just by heat, but by specific biomarkers as well, the researchers said.
A microprocessor reads the data from the sensors and can release drug on demand from its carriers by heating the gel.
The entire construct is attached to a transparent medical tape to form a flexible bandage less than 3 mm thick. Components were selected to keep the bandage cheap and disposable, except for the microprocessor, which can be re-used.
The researchers noted that smart bandages could provide real time monitoring and delivery of treatment with limited intervention from the patient or caregivers.
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2001 Parliament attack anniversary: Vice Prez, PM Modi, MPs pay tributes to fallen heroes
New Delhi (PTI): Vice President C P Radhakrishnan on Saturday led Parliamentarians in paying floral tributes to those who died fending off terrorists who attacked the Parliament House in 2001.
On the 24th anniversary of the attack, Prime Minister Narendra Modi and Radhakrishnan, who is also the Rajya Sabha Chair, were among the first to offer tributes.
A brief function is held outside the now old Parliament building (Samvidhan Sadan) every December 13 to mark the day.
CISF personnel presented a salute or "samman guard" at the venue, after which a moment of silence was observed to mark the anniversary. Till 2023, the CRPF used to offer 'salami shastra' (present arms).
Congress leader Sonia Gandhi, Leader of the Opposition in the Lok Sabha Rahul Gandhi, and his sister Priyanka Gandhi Vadra, a senior party leader, were also present at the event. Union ministers Kiren Rijiju, Jitendra Singh and Arjun Ram Meghwal also lined up to offer flower petals at the photographs of the personnel who went down foiling the attack.
Lok Sabha Speaker Om Birla is in Latur to attend the funeral of former speaker of the Lower House of Parliament and ex-Union minister Shivraj Patil.
The attack was carried out by five armed terrorists, but personnel from the now former Parliament Security Service, CRPF and Delhi Police foiled the attack, with no terrorist being able to enter the building.
Six Delhi Police personnel, two Parliament Security Service personnel, a gardener and a TV video journalist were killed in the attack. All five terrorists were gunned down in the forecourt of the then Parliament building.
