Novel regenerative bandage may heal diabetics' wounds faster
New York, June 12: Your painful, hard-to-treat sores may soon be a thing of the past as scientists have developed a regenerative bandage that may quickly heal them without using drugs, an advance which may help make healing of wounds in diabetics faster.
The study, published in the journal Proceedings of the National Academy of Sciences, showed that the bandage healed diabetic wounds 33 per cent faster than one of the most popular bandages currently on the market.
"The novelty is that we identified a segment of a protein in skin that is important to wound healing, made the segment and incorporated it into an antioxidant molecule that self-aggregates at body temperature to create a scaffold that facilitates the body's ability to regenerate tissue at the wound site," said lead author Guillermo Ameer from the Northwestern University in Illinois, US.
The logic behind the regenerative bandage is laminin -- a protein found in most of the body's tissues including the skin.
Laminin sends signals to cells, encouraging them to differentiate, migrate and adhere to one another. The team identified a segment of laminin -- 12 amino acids in length -- called A5G81 that is critical for the wound-healing process.
They incorporated A5G81 into an antioxidant hydrogel bandage that it previously developed in the laboratory. The antioxidant nature also helps counters inflammation.
Hydrogel liquid can form the exact shape of the wound which makes this bandage better than others.
"Wounds have irregular shapes and depths. Our liquid can fill any shape and then stay in place. Other bandages are mostly based on collagen films or sponges that can move around and shift away from the wound site," Ameer said.
The team also used animal models to test the effectiveness and found no adverse effects of the bandage on the animals.
Ameer also added that their bandage can be rinsed off with cool saline, so the regenerating tissue remains undisturbed.
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'The Ba**ds of Bollywood’ mirrors my life, damages my reputation: Sameer Wankhede tells Delhi HC
New Delhi: IRS officer Sameer Wankhede has submitted his reply to the Delhi High Court in the defamation case he filed against Red Chillies Entertainment, the production company owned by actor Shah Rukh Khan. The case pertains to the recently released series The Ba**ds of Bollywood*, which Wankhede claims has defamed him.
In his statement to the court, Wankhede asserted that the show’s portrayal of a police officer is clearly based on him and has caused serious harm to his public image. He cited four key reasons supporting his claim.
First, he said the character in question bears physical similarities to him, including facial and body features. Second, he noted that the character’s working style and mannerisms closely resemble his own.
Third, Wankhede highlighted that the officer in the show is depicted making a high-profile arrest involving a major film personality, which he said directly mirrors his own involvement in the Aryan Khan drug case.
Fourth, he pointed out that the character frequently uses the phrase “Satyameva Jayate,” a motto he himself had used during media interactions in the course of that investigation. He argued that using the national motto in such a context cannot be dismissed as creative expression or humour.
Wankhede also referred to an interview in which Aryan Khan allegedly admitted that the show was “inspired by some real events.” This, he said, contradicts Red Chillies Entertainment’s claim that The Ba**ds of Bollywood* is purely fictional.
He further alleged that the tone and intent of the series indicate personal and institutional vendetta, aimed at discrediting and defaming him rather than engaging in artistic storytelling.
Wankhede informed the court that the fallout from the show has affected his family, with his wife and sister receiving abusive and vulgar messages online.
Rejecting Red Chillies’ argument that he is a “thin-skinned” officer, Wankhede said that a public servant cannot be expected to tolerate false and damaging portrayals simply because of his position. He emphasized that his legal action seeks to protect the constitutional rights and dignity of both himself and his family.
