Novel regenerative bandage may heal diabetics' wounds faster
New York, June 12: Your painful, hard-to-treat sores may soon be a thing of the past as scientists have developed a regenerative bandage that may quickly heal them without using drugs, an advance which may help make healing of wounds in diabetics faster.
The study, published in the journal Proceedings of the National Academy of Sciences, showed that the bandage healed diabetic wounds 33 per cent faster than one of the most popular bandages currently on the market.
"The novelty is that we identified a segment of a protein in skin that is important to wound healing, made the segment and incorporated it into an antioxidant molecule that self-aggregates at body temperature to create a scaffold that facilitates the body's ability to regenerate tissue at the wound site," said lead author Guillermo Ameer from the Northwestern University in Illinois, US.
The logic behind the regenerative bandage is laminin -- a protein found in most of the body's tissues including the skin.
Laminin sends signals to cells, encouraging them to differentiate, migrate and adhere to one another. The team identified a segment of laminin -- 12 amino acids in length -- called A5G81 that is critical for the wound-healing process.
They incorporated A5G81 into an antioxidant hydrogel bandage that it previously developed in the laboratory. The antioxidant nature also helps counters inflammation.
Hydrogel liquid can form the exact shape of the wound which makes this bandage better than others.
"Wounds have irregular shapes and depths. Our liquid can fill any shape and then stay in place. Other bandages are mostly based on collagen films or sponges that can move around and shift away from the wound site," Ameer said.
The team also used animal models to test the effectiveness and found no adverse effects of the bandage on the animals.
Ameer also added that their bandage can be rinsed off with cool saline, so the regenerating tissue remains undisturbed.
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Oppn leaders expresses outrage over killing of 'OBC' man with brick in Meerut
Meerut (UP) (PTI): Samajwadi Party chief Akhilesh Yadav and Bahujan Samaj Party (BSP) president Mayawati have condemned the killing of a backward class youth in the Sardhana area of Meerut.
Both leaders on Sunday urged the government to be vigilant and proactive to prevent such crimes.
In a post on X, Mayawati said that the January 5 killing of a youth belonging to the Kashyap community, categorised under the Other Backward Classes (OBC), deserved the strongest condemnation.
She stressed that anti-social and criminal elements must have fear of the law.
In his post, SP chief said, "We raise our voice on behalf of the entire PDA community against the heinous act committed by goons who burned a young man from the Kashyap community alive in Jwalagarh, in the Sardhana area."
Responding to the posts, the Meerut police said the it was not a recent case and that had registered a murder FIR and solved the crime within 24 hours of the incident.
The accused, they said, is a minor who was produced before the Juvenile Justice Board and sent to a child reform home.
According to the police, the incident took place on January 5 on the Akhepur-Rardhana Road.
The victim was identified as Rohit alias Sonu, 28, a resident of the Kila locality in Muzaffarnagar city.
An investigation revealed that the crime followed an argument over loud music being played in a tempo. The accused, a 16-year-old tempo driver, allegedly assaulted Rohit with a brick, killing him.
Circle Officer (Sardhana) Ashutosh Kumar said the accused first befriended Rohit, made him consume liquor while he himself drank an energy drink and later struck him on the head with a brick.
To conceal his identity, the accused dragged the body about 15 metres to a spot near a school wall and set it on fire using clothes, dry leaves, and oil.
The incident came to light when a school watchman noticed a fire late that night and informed the police. The body was identified the next day.
Family members said Rohit worked as a confectioner in Mumbai and had come to his village to look for a bride.
The police said the accused was identified through a barcode on a liquor pouch recovered from the spot and CCTV footage from a liquor shop.
