Pregnancy history may be tied to Alzheimer's disease
Seoul, July 22 : Women, take note. Your history of pregnancy may affect the risk of Alzheimer's disease decades later, a new study has found.
The study, published in journal Neurology, found that women who give birth to five or more children may be more likely to develop Alzheimer's disease than women who have fewer births.
"Estrogen levels double by the eighth week of pregnancy before climbing to up to 40 times the normal peak level," said co-author Ki Woong Kim frrom the Seoul National University.
"If these results are confirmed in other populations, it is possible that these findings could lead to the development of hormone-based preventive strategies for Alzheimer's disease based on the hormonal changes in the first trimester of pregnancy," Kim added.
For the study, the researchers combined the data from two independent population-based studies with a total of 3,549 women.
Women -- who were an average age of about 71 at the start of the study -- provided information on their reproductive history. They took the diagnostic examination after an average of 46 years from their first childbirth.
During that time, the participants took tests of their memory and thinking skills to see whether they had developed Alzheimer's disease or its precursor, mild cognitive impairment.
The study found that a total of 118 women developed Alzheimer's disease and 896 women developed mild cognitive impairment.
The researchers also found that women who had given birth to five or more children were 70 per cent more likely to develop Alzheimer's disease than women who gave birth to fewer children.
Women who had experienced an incomplete pregnancy were about half as likely to develop Alzheimer's disease as women who had never had an incomplete pregnancy.
Of the 2,375 women who had an incomplete pregnancy, 47 developed Alzheimer's disease, compared to 71 of the 1,174 women who never had an incomplete pregnancy, they added.
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Karnataka cabinet approves formation of separate Dharwad Municipal Corporation
Bengaluru: The Karnataka Cabinet has approved a formation of separate Dharwad city corporation. Alongside, a 15% hike in fares across the four state transport corporations was also approved. The revised fares will come into effect on January 5.
Law and Parliamentary Affairs Minister H.K. Patil, addressing the media at the Committee Hall of Vidhana Soudha, provided details about the decision. He explained that the last fare revision for BMTC was a decade ago when diesel cost Rs 60.98 per litre. Since then, operational costs have risen significantly.
Diesel expenditure for the four corporations has increased from Rs 9.16 crore to Rs 13.21 crore, and personnel costs have grown from Rs 12.85 crore to Rs 18.36 crore. The daily operational burden now stands at Rs 9.56 crore. The fare hike is expected to generate an additional Rs 74.85 crore in monthly revenue without burdening the state exchequer, as Rs 5,015 crore has already been allocated for the Shakti Yojana this fiscal year.
Minister Patil announced that the Cabinet has decided to bifurcate the Hubballi-Dharwad Municipal Corporation into two independent municipal bodies.
The Cabinet approved the construction of a fishing port in Hejamady village, Udupi, with a revised estimate of Rs 209.13 crore. Additionally, Rs 84.57 crore has been sanctioned for the modernization and dredging of fishing ports.
In a move to strengthen cow shelters, Rs 10.50 crore has been allocated for projects in 14 districts. The Cabinet also approved constructing a building for Visvesvaraya Technical University in Chikkaballapur district at Rs 149.75 crore.
The Cabinet sanctioned a state-of-the-art bus stand in Bannimantap, Mysuru, at a cost of Rs 120 crore. Spread over 14 acres, the facility will include a divisional office, bus units, and commercial shops.
Approval was also granted to utilize Rs 137.85 crore, provided by the Union Finance Ministry under the Special Capital Assistance Scheme, for capital expenditure.
The Kalyana Karnataka Regional Development Board will use Rs 56.92 crore from its SCP/TSP scheme to supply bed sheets, mosquito nets, and clothing to government residential schools and hostels.
The Cabinet approved Rs 100 crore to construct new buildings for 200 veterinary institutions currently housed in rented or dilapidated structures, using NABARD assistance.
In Davangere, a site was allotted to the Karnataka Working Journalists' Association for constructing a civic facility. A plot in Avaragere village was also leased for 30 years at a concessional rate to Nayaka Vidyarthi Nilaya.
