Vaccinated patients less likely to need critical care due to Omicron infection: Study
Los Angeles (PTI): Vaccinated adults have a lower risk of severe illness due to Omicron variant of coronavirus, and are less likely to land in intensive care compared with unvaccinated patients, a US study suggests.
The study, published in a weekly report by the US Centers for Disease Control and Prevention (CDC), also found that during the Omicron period fewer patients died while hospitalised, compared with those admitted when the Delta variant was dominant.
"Overall, the Omicron-period group had a lower likelihood of being admitted to the intensive care unit (ICU) and were also less likely to require invasive mechanical ventilation compared with the Delta-period group," said Matthew Modes, a pulmonologist at Cedars-Sinai Medical Centre in the US, and co-first author of the study.
The researchers looked at the characteristics of 339 patients hospitalised with COVID-19 at Cedars-Sinai Medical Center from July to September of 2021, when the Delta variant of SARS-CoV-2 was dominant.
They compared that group with 737 patients admitted with COVID-19 during December 2021-January 2022, when the Omicron variant was most prevalent.
Clinical information was gathered from the electronic health records of the patients in the study.
The analysis shows that a greater portion of the patients hospitalised during Omicron were vaccinated as compared to patients hospitalised during the summer of 2021 when the Delta variant predominated.
"In addition to the protection that vaccination offered people admitted to the hospital when Omicron dominated, we saw that the addition of a booster dose appeared to be particularly important in reducing the severity of illness, especially among older adults," said senior author of the study Peter Chen, from Cedars-Sinai.
"Unvaccinated patients hospitalised with COVID-19 during the Omicron variant dominance still had a higher chance of being admitted with serious complications and appeared to be at higher risk for the development of respiratory failure, compared with vaccinated patients," said Chen.
The researchers noted that vaccination, including a booster dose for those who are fully vaccinated, remains critical for mitigating the risk of severe illness associated with SARS-CoV-2 infection.
"A clear pattern emerges if you take just the Omicron-period patients and compare their vaccination status against the percentage of them who ended up in the ICU," said Michael Melgar, a co-first author of the study and a medical officer with the CDC.
"The more vaccinated someone is -- from unvaccinated, partially vaccinated, fully vaccinated without a booster dose to fully vaccinated with a booster dose -- the better the outcome for the patient," Melgar added.
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UDF leaders see local body poll trends as pointer to 2026 Assembly elections in Kerala
Thiruvananthapuram (PTI): Buoyed by the strong performance of the Congress-led UDF in the local body polls, KPCC president Sunny Joseph said on Saturday that the front's results indicated the people had rejected the LDF government.
According to early trends, the UDF was leading in more grama panchayats, block panchayats, municipalities and corporations than the LDF.
The local body polls were held in two phases in the state earlier this week.
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Speaking to reporters here, Joseph said the people of Kerala had extended their support to the UDF.
"We could expose the LDF government’s anti-people stance and the people understood it. The LDF’s fake propaganda was rejected by the people. The UDF is moving towards a historic victory," he said.
He said a united effort, proper preparations, good candidate selection and hard work had resulted in the Congress and the UDF’s victory in the elections.
Asked about the prospects in the Thiruvananthapuram Corporation, Joseph said the party was studying the matter and would comment later.
LDF convenor T P Ramakrishnan said the results would be closely examined.
According to him, the government had done everything possible for the people.
"Why such a verdict happened will be examined at the micro level. People’s opinion will be considered and further steps will be taken," he said.
He added that decisions would be taken after analysing the results. "If any corrective measures are required, we will initiate them and move forward," he said.
AICC leader K C Venugopal said the results showed that people had begun ousting those who, he alleged, were responsible for the loss of gold at Lord Ayyappa’s temple.
"This trend will continue in the Assembly elections as well. It is an indication that the people are ready to bring down the LDF government," he said.
Venugopal said the UDF had registered victories even in CPI(M) and LDF strongholds.
"I congratulate all UDF workers for their hard work. Congress workers and leaders worked unitedly," he said.
Referring to remarks made by Chief Minister Pinarayi Vijayan against the Congress on polling day, Venugopal said the voters had responded through the verdict.
"I do not know whether the chief minister understands that the people are against him. Otherwise, he does not know the sentiment of the people. The state government cannot move an inch further," he said.
He said the results indicated a strong comeback for the UDF in Kerala.
Asked whether the Sabarimala gold loss issue had affected the LDF in the local polls, Venugopal said the CM and the CPI(M) state secretary did not take the issue seriously.
"We took a strong stand on the matter. The BJP played a foul game in it," he alleged.
On the BJP's role in the local body elections, Venugopal alleged that the party operated with the CPI(M) 's tacit support.
"The CPI(M) supported the central government on issues such as PM-SHRI, labour codes and corruption in national highway construction. The CPI(M) is facing ideological decline, and the state government’s policies are against the party’s own decisions," he said.
Meanwhile, LDF ally Kerala Congress (M) leader Jose K Mani said the party could not win all the wards it had expected in the elections.
He congratulated winners from all parties and said the party would closely examine the losses and identify shortcomings. "Later, we will take corrective measures," he added.
Senior Congress leader and MP Rajmohan Unnithan said the trends in the local body elections indicated that the UDF would return to power in the 2026 Assembly elections.
"We will win 111 seats as in 1977 and return to power in 2026. The anti-government sentiment of the people is reflected in the elections," he said.
Unnithan said the people were disturbed and unhappy with the present government.
"The trend indicates the end of the LDF government," he added.
CPI(M) MLA M M Mani said the people had shown ingratitude towards the LDF despite benefiting from welfare schemes.
"After receiving all welfare schemes and living comfortably, people voted against us due to some temporary sentiments. Is that not ingratitude," he asked.
Mani said no such welfare initiatives had taken place in Kerala earlier.
"People are receiving pensions and have enough to eat. Even after getting all this, they voted against us. This is what can be called ingratitude," he said.
Muslim League state president Panakkad Sayyid Sadiq Ali Shihab Thangal said the results were beyond expectations.
"The outcome points towards the Secretariat in Thiruvananthapuram, indicating that a change of government is imminent. We are going to win the Assembly election," he said.
