New Delhi, July 19: Love to gorge on beef jerky, salami, hot dogs and other processed meat as part of your evening snacks daily? Beware, these processed meats laced with chemicals such as nitrates, to preserve them from spoilage, may contribute to mania -- an abnormal mood state characterized by hyperactivity, euphoria and insomnia, a study has found.

The findings showed that people hospitalised for an episode of mania had more than three times the odds of having ever eaten nitrate-cured meats than people without a history of a serious psychiatric disorder.

"We looked at a number of different dietary exposures and cured meat really stood out. It wasn't just that people with mania have an abnormal diet," said lead author Robert Yolken, Professor at the Johns Hopkins University in the US.

Nitrates have long been used as preservatives in cured meat products and have been previously linked to some cancers and neurodegenerative diseases, so Yolken suspected they may also explain the link to mood states such as mania.

Further, in experiments on rats, those who received the jerky showed irregular sleeping patterns and hyperactivity similar to that seen in patients with mania -- increased activity during normal sleep times and in new environments.

However, when the animals were fed on nitrate-free meat, they behaved similarly to a control group.

"It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated maniac episodes," explained Seva Khambadkone, doctoral student at the varsity.

"Our results suggest that nitrated cured meat could be one environmental player in mediating mania," Khambadkone added.

Moreover, the animals with nitrate in their diet had different patterns of bacteria living in their intestines than the other rats and had differences in several molecular pathways in the brain that have been previously implicated in bipolar disorder.

"Future work on this association could lead to dietary interventions to help reduce the risk of manic episodes in those who have bipolar disorder or who are otherwise vulnerable to mania," Yolken said.

 

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Washington, Oct 31: Sending Diwali greetings, former president Donald Trump, who is the Republican presidential candidate, on Thursday condemned the attack on Hindus in Bangladesh, vowed to strengthen ties with India and described Prime Minister Narendra Modi as his good friend.

Bangladesh, he said, remains in a total state of chaos and alleged that his Democratic rival Vice President Kamala Harris and her boss President Joe Biden have ignored Hindus across the world and in America.

“I strongly condemn the barbaric violence against Hindus, Christians, and other minorities who are getting attacked and looted by mobs in Bangladesh, which remains in a total state of chaos,” Trump said in a post on Truth Social.

This is for the first time that Trump has spoken on the issue of Bangladesh. Hundreds of Hindus were killed in July-August in Bangladesh when a students’ agitation turned into massive protests leading to then prime minister Sheikh Hasina to flee the country on August 5.

“It would have never happened on my watch. Kamala and Joe have ignored Hindus across the world and in America. They have been a disaster from Israel to Ukraine to our own Southern Border, but we will Make America Strong Again and bring back Peace through Strength,” he said.

“We will also protect Hindu Americans against the anti-religion agenda of the radical left. We will fight for your freedom. Under my administration, we will also strengthen our great partnership with India and my good friend, Prime Minister Modi,” Trump said.

“Kamala Harris will destroy your small businesses with more regulations and higher taxes. By contrast, I cut taxes, cut regulations, unleashed American energy, and built the greatest economy in history. We will do it again, bigger and better than ever before and we will Make America Great Again,” he said.

“Also, Happy Diwali to All. I hope the Festival of Lights leads to the Victory of Good over Evil,” said the former president, who is in a close fight with Harris for the November 5 presidential elections.