Beef jerky, processed meats linked to manic episodes: Study
New Delhi, July 19: Love to gorge on beef jerky, salami, hot dogs and other processed meat as part of your evening snacks daily? Beware, these processed meats laced with chemicals such as nitrates, to preserve them from spoilage, may contribute to mania -- an abnormal mood state characterized by hyperactivity, euphoria and insomnia, a study has found.
The findings showed that people hospitalised for an episode of mania had more than three times the odds of having ever eaten nitrate-cured meats than people without a history of a serious psychiatric disorder.
"We looked at a number of different dietary exposures and cured meat really stood out. It wasn't just that people with mania have an abnormal diet," said lead author Robert Yolken, Professor at the Johns Hopkins University in the US.
Nitrates have long been used as preservatives in cured meat products and have been previously linked to some cancers and neurodegenerative diseases, so Yolken suspected they may also explain the link to mood states such as mania.
Further, in experiments on rats, those who received the jerky showed irregular sleeping patterns and hyperactivity similar to that seen in patients with mania -- increased activity during normal sleep times and in new environments.
However, when the animals were fed on nitrate-free meat, they behaved similarly to a control group.
"It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated maniac episodes," explained Seva Khambadkone, doctoral student at the varsity.
"Our results suggest that nitrated cured meat could be one environmental player in mediating mania," Khambadkone added.
Moreover, the animals with nitrate in their diet had different patterns of bacteria living in their intestines than the other rats and had differences in several molecular pathways in the brain that have been previously implicated in bipolar disorder.
"Future work on this association could lead to dietary interventions to help reduce the risk of manic episodes in those who have bipolar disorder or who are otherwise vulnerable to mania," Yolken said.
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MP: 7-year-old girl raped and murdered; minor relative detained
Barwani (MP), Jan 28 (PTI) Police on Wednesday detained a 17-year-old relative of a seven-year-old girl in Barwani district of Madhya Pradesh for allegedly raping her and killing her by throwing her into a canal, a police official said.
Superintendent of Police Jagdish Dawar told reporters that the body of the child was recovered from the Indira Sagar Canal on January 26, following information from residents of a village in the Rajpur police station area of the district.
He said the post-mortem report concluded severe injuries to the girl’s private parts and attributed her death to drowning.
Dawar said a 17-year-old boy, a close relative of the girl, has been detained in connection with the rape-murder.
The teenager told the police that he kidnapped the girl from her home on the night of January 25 while her family members were asleep, took her to a nearby canal and raped her, according to the official.
When the girl started screaming during the sexual assault, the minor boy allegedly threw her into the canal, with the intention of killing her. The child drowned in the water body, the official said.
The detained minor will be produced in a juvenile court.
A case has been registered under the Protection of Children from Sexual Offences Act and the Bharatiya Nyaya Sanhita, and an investigation is underway, he added.
