Beef jerky, processed meats linked to manic episodes: Study
New Delhi, July 19: Love to gorge on beef jerky, salami, hot dogs and other processed meat as part of your evening snacks daily? Beware, these processed meats laced with chemicals such as nitrates, to preserve them from spoilage, may contribute to mania -- an abnormal mood state characterized by hyperactivity, euphoria and insomnia, a study has found.
The findings showed that people hospitalised for an episode of mania had more than three times the odds of having ever eaten nitrate-cured meats than people without a history of a serious psychiatric disorder.
"We looked at a number of different dietary exposures and cured meat really stood out. It wasn't just that people with mania have an abnormal diet," said lead author Robert Yolken, Professor at the Johns Hopkins University in the US.
Nitrates have long been used as preservatives in cured meat products and have been previously linked to some cancers and neurodegenerative diseases, so Yolken suspected they may also explain the link to mood states such as mania.
Further, in experiments on rats, those who received the jerky showed irregular sleeping patterns and hyperactivity similar to that seen in patients with mania -- increased activity during normal sleep times and in new environments.
However, when the animals were fed on nitrate-free meat, they behaved similarly to a control group.
"It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated maniac episodes," explained Seva Khambadkone, doctoral student at the varsity.
"Our results suggest that nitrated cured meat could be one environmental player in mediating mania," Khambadkone added.
Moreover, the animals with nitrate in their diet had different patterns of bacteria living in their intestines than the other rats and had differences in several molecular pathways in the brain that have been previously implicated in bipolar disorder.
"Future work on this association could lead to dietary interventions to help reduce the risk of manic episodes in those who have bipolar disorder or who are otherwise vulnerable to mania," Yolken said.
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Will Champai Soren become a game-changer for BJP in Jharkhand polls?
Ranchi: Champai Soren, a prominent figure in Jharkhand’s statehood movement, is contesting the 2024 assembly elections from Seraikela, a seat he has consistently held since 1991.
However, there is a surprising shift in his political journey this year. Having resigned from the Jharkhand Mukti Morcha (JMM) earlier this year, Soren is now representing the BJP, a move that could significantly impact the electoral dynamics in the state.
Soren’s switiching is seen as a strategic benefit for the saffron party, which has been working to expand its appeal among Jharkhand’s tribal communities, a demographic traditionally aligned with the JMM. His departure from the JMM, led by Shibu Soren and his son Hemant Soren, was fueled by dissatisfaction with the state government’s policies, which he claimed had failed to address tribal concerns.
Also known as "Jharkhand’s Tiger" for his instrumental role in the statehood movement of the 1990s, Champai Soren has respect and influence among tribal voters. His decision to switch the party could be a turning point in the BJP’s efforts to gain a stronger hold in a state where tribal votes often decide the outcome.
