First 3D-printed human corneas can aid transplants
London, May 30: In a first, British scientists have 3D printed human corneas that could cut down shortage of eye donors available for transplant.
In the research, researchers from Britain's Newcastle University, mixed stem cells (human corneal stromal cells) from a healthy donor cornea with alginate and collagen to create a solution that could be printed or a "bio-ink".
Using a simple low-cost 3D bio-printer, the bio-ink was successfully extruded in concentric circles to form the shape of a human cornea. It took less than 10 minutes to print.
"Our unique gel -- a combination of alginate and collagen -- keeps the stem cells alive whilst producing a material which is stiff enough to hold its shape but soft enough to be squeezed out the nozzle of a 3D printer," said lead author Che Connon, a professor at the varisty.
The results published in the journal, Experimental Eye Research, also stated that the stem cells could culture -- or grow.
"...we have a ready to use bio-ink containing stem cells allowing users to start printing tissues without having to worry about growing the cells separately," Connon added.
According to the researchers, there is a significant shortage of corneas available to transplant, with 10 million people worldwide requiring surgery to prevent corneal blindness as a result of diseases such as trachoma, an infectious eye disorder.
Further, the study also demonstrated that the cornea could also be built to match a patient's unique specifications.
The dimensions of the printed tissue were originally taken from an actual cornea. By scanning a patient's eye, they could use the data to rapidly print a cornea which matched the size and shape, the team explained.
"...what we have shown is that it is feasible to print corneas using coordinates taken from a patient eye and that this approach has potential to combat the world-wide shortage," Connon said.
However, the researchers admitted that further investigations on 3D printed corneas are needed before they could be used in transplants.
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Ex-Army officer assaulted, robbed at gunpoint by woman he met through matrimonial website
Mathura(UP), Apr 5 (PTI): A retired Army colonel from Haryana has filed a police complaint here, alleging that he was held hostage, assaulted, looted and forced to participate in an "obscene video" at gunpoint with a woman he met through a matrimonial website, police said on Saturday.
The woman from Mathura, who was allegedly in on the plan to rob him, was working with other accomplices, the ex-armyman said in his complaint filed on Thursday.
According to Barsana Station House Officer (SHO) Raj Kamal Singh, Colonel Rajneesh Soni (retired), a resident of Gurugram, reported that he was contacted by a woman from Barsana on a matrimonial website in January. The woman allegedly agreed to marry him, and they began communicating.
The woman allegedly persuaded the colonel to visit Barsana on January 25, requesting that he visit the Radharani temple. When he arrived, she arranged for his stay at a guest house and took him on a tour of the area, including a visit to the temple, the complainant said.
After returning to the guest house, the woman and her accomplices allegedly told the colonel that her brother had been involved in an accident and they needed to leave immediately. They then led him to a waiting car.
"Once outside the town limits, the colonel alleges that he was attacked by the occupants of the car. They seized his phone, physically assaulted him, and forced him to contact relatives and friends to transfer money," the SHO said.
"He was then taken back to the guest house, where he was allegedly forced to participate in obscene videos and photographs at gunpoint. He was threatened that the videos would be made public if he reported the incident," the officer said.
The colonel has alleged that his purse, bag, gold chain, debit card and Rs. 12,000 in cash were stolen from the guest house.
After an unsuccessful attempt at locating the perpetrators himself, the colonel finally reported the incident to the Barsana police two days ago, he said.
"A case has been registered under relevant sections of the BNS and all facts are being investigated. Further action will be taken as per facts found in the investigation," the SHO said.
