Ketamine can cut depression, suicidality rapidly: Study
New York, April 16: Recreational drug Ketamine is likely to have fast-acting benefits in treating symptoms of depression as well as reducing suicidal thoughts, say researchers, including one of an Indian-origin.
The findings of the trial, published in the American Journal of Psychiatry, showed use of Ketamine, also licensed as an anaesthetic, through a nasal spray, led to significant improvements in depressive symptoms and reduction in suicidal thoughts in the first 24 hours.
Esketamine could be an important treatment to bridge the gap as it can help in the rapid treatment compared to the delayed effects of most common antidepressants, which take four to six weeks to become fully effective, said Jaskaran B. Singh, from the Janssen Research & Development in San Diego, US.
The results support nasal spray esketamine as a possible effective rapid treatment for depressive symptoms in patients assessed to be at imminent risk for suicide, the researchers noted.
For the study, a small group of participants randomly assigned to one of two groups - either receiving esketamine or placebo twice a week for four weeks, and found a significant improvement in depression scores and decreased suicidal ideation in the esketamine group compared to the placebo group at four hours and at 24 hours.
However, at 25 days, the effects had levelled out.
While there esketamine dependence or misuse was not observed in the trial, the researchers suggested for effective controls on the distribution and use of ketamine.
They argued that steps to control the use of ketamine would not be aimed at preventing its use for beneficial purposes but would allow for treatment to "continue to be available to those with need, while the population that is at-risk for abuse is protected from an epidemic of misuse."
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Karnataka: Paramedical student attempts suicide after 'harassment', ex-boyfriend held
Hubballi (PTI): A 20-year-old paramedical college student attempted suicide by consuming pills after allegedly being harassed and blackmailed with her photographs by an acquaintance, police said on Wednesday.
Following the incident on Tuesday, the 23-year-old accused, who was previously in a relationship with her, was arrested, they added.
The matter came to light when the Karnataka Medical College and Research Institute (KMCRI) informed the Vidyanagar police station about the woman’s suicide attempt, police said.
According to police, the second-year student attempted suicide in her women’s hostel after enduring constant "harassment and blackmail".
Citing a preliminary inquiry, a senior police officer stated that the woman and the accused were previously in a relationship. However, after their breakup, he allegedly began harassing and blackmailing her with her photographs.
"The woman's parents filed a complaint accusing the suspect of physical assault, mental harassment, and blackmail using her photographs and messages. Both the woman and the accused hail from Kundgol town, but for the past few months, he had been trying to harass her," the senior police officer said.
Based on the complaint, an FIR was registered, and the accused was arrested. The case will be investigated thoroughly, he added.
The woman is now out of danger, police said, adding that further investigation is underway.
