Wireless device to detect heart dysfunction in cancer survivors
New York, June 23 : Scientists have designed a novel wireless device which may accurately detect heart dysfunction in children who have survived cancer.
Childhood cancer survivors are advised to undergo screening for the detection of heart dysfunction because of known anthracycline-induced cardiotoxicity.
However, screening with echocardiography -- the standard of care for monitoring heart function -- can be highly variable and limited.
Another alternative is cardiac magnetic resonance (CMR) imaging, which is expensive and is not widely accessible.
In the study, the team tested Vivio -- a prototype handheld instrument which collects pulse waves and phonocardiogram data from the carotid artery. The results showed that the device was accurate and it displayed a low false-negative rate as compared to CMR imaging.
"This study is the first step in thinking about new paradigms of long-term monitoring and care delivery for cancer survivors who are at risk for severe and life-threatening health conditions," said Saro Armenian, Director at City of Hope National Medical Centre in California.
The study, published in the journal Clinical Cancer Research, involved data from 191 patients exposed to anthracycline chemotherapy.
The data of the participants was collected using Vivio which then streamed wirelessly to a compatible device such as a smart phone or e-tablet.
This mobile health platform negates the need for result interpretation and allows for real-time monitoring of heart health, explained Armenian.
Using a specialised algorithm, Vivio measures the left ventricular ejection fraction (LVEF), which is commonly used to assess heart function and measures the percentage of blood ejected from the left ventricle of the heart, Armenian added.
However, the author said that Vivio is not currently intended to replace echocardiography or CMR imaging.
"One possible implementation of Vivio could be for preliminary screening," Armenian explained.
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Jhansi fire: Nurse's heroic efforts helped save over dozen babies
Lucknow/Jhansi (UP), Nov 17: Nurse Megha James was on duty when the fire broke out at the Jhansi hospital and she threw herself headlong into the rescue efforts, playing a hero's role by saving several babies.
Even when her salwar got burned, she refused to give up and was able to evacuate 14-15 babies with others' help.
"I had gone to take a syringe to give an injection to a child. When I came back, I saw that the (oxygen) concentrator had caught fire. I called the ward boy, who came with the fire extinguisher and tried to put it out. But by then, the fire had spread," James said.
Ten babies perished in a fire that broke out at the Neonatal Intensive Care Unit of the Maharani Laxmi Bai Medical College in Jhansi Friday night.
Faced with an enormous blaze, James's mind worked with a frenetic speed, to the extent she cared little about burning herself.
"My chappal caught fire and I burned my foot. Then my salwar caught fire. I removed my salwar and discarded it. At that time, my mind was virtually not working," she told PTI Videos.
James just wore another salwar and went back to the rescue operation.
"There was a lot of smoke, and once the lights went out, we could not see anything. The entire staff brought out at least 14-15 children. There were 11 beds in the ward with 23-24 babies," she said.
Had the lights not gone out they could have saved more children, James said. "It all happened very suddenly. None of us had expected it."
Assistant Nursing Superintendent Nalini Sood praised James's valour and recounted bits from how the rescue operation was carried out.
"The hospital staff broke the glasses of the NICU ward to evacuate the babies. It was then Nurse Megha's salwar caught fire. Instead of caring for her safety, she stayed there to rescue the babies and handed them over to people outside," she said.
Sood said James is currently undergoing treatment at the same medical college. She said she did not know the extent of her burns.
"The rescued babies were shifted to a ward very close to the NICU ward… When I recall the scene, I feel like crying," she said.
Dr Anshul Jain, the head of the anaesthesiology department at the medical college, explained the standard rescue operation and claimed the hospital followed the protocol to the T.
"In the triage process during an ICU evacuation, the policy is to evacuate less-affected patients first. The rationale behind this approach is that patients requiring minimal support can be relocated quickly, enabling a larger number of evacuations to be completed in a shorter time.
"In contrast, patients on ventilators or requiring high oxygen support demand more time and resources for evacuation," he said.
"This principle was successfully implemented in Jhansi, playing a significant role in saving many lives," Jain said.
A newborn rescued from the fire died due to illness on Sunday, Jhansi District Magistrate Avinash Kumar said.
