United Nations/Geneva, Jun 6: A total of 780 laboratory-confirmed cases of monkeypox have been reported or identified since May 13 and as of June 2 from 27 countries across four WHO regions that are not endemic for the monkeypox virus, the World Health Organisation has said.
The UN's health agency said that while epidemiological investigations are ongoing, most reported cases so far have been presented through sexual health or other health services in primary or secondary health care facilities and have involved mainly, but not exclusively, men who have sex with men (MSM).
While the West African clade of the virus has been identified from samples of cases so far, most confirmed cases with travel history reported travel to countries in Europe and North America, rather than West or Central Africa where the monkeypox virus is endemic.
The confirmation of monkeypox in persons who have not travelled to an endemic area is atypical, and even one case of monkeypox in a non-endemic country is considered an outbreak. While most cases are not associated with travel from endemic areas, Member States are also reporting small numbers of cases in travellers from Nigeria, as has been observed before, it said on Sunday.
Monkeypox endemic countries are Cameroon, the Central African Republic, the Democratic Republic of the Congo, Gabon, Ghana (identified in animals only), Cote d'Ivoire, Liberia, Nigeria, the Republic of the Congo, and Sierra Leone. Benin and South Sudan have documented importations in the past. Countries currently reporting cases of the West African clade are Cameroon and Nigeria, the WHO said.
The sudden and unexpected appearance of monkeypox simultaneously in several non-endemic countries suggests that there might have been undetected transmission for some unknown duration of time followed by recent amplifier events.
WHO assesses the risk at the global level as moderate considering this is the first time that many monkeypox cases and clusters are reported concurrently in non-endemic and endemic countries in widely disparate WHO geographical areas.
WHO said it continues to receive updates on the situation in endemic countries. As of June 2, 780 laboratory-confirmed cases have been notified to WHO under the International Health Regulations (IHR) or identified by WHO from official public sources in 27 non-endemic countries in four WHO Regions. This represents an increase of 523 laboratory-confirmed cases (+203%) since the Disease Outbreak News of 29 May, when a total of 257 cases were reported.
As of June 2, there have been no deaths associated with the current monkeypox outbreak in non-endemic countries, however, cases and deaths continue to be reported from endemic countries.
While investigations are ongoing, preliminary data from polymerase chain reaction (PCR) assays indicate that the monkeypox virus strains detected in Europe and other non-endemic areas belong to the West African clade.
The majority of cases were reported from the WHO European Region (20 Countries). Confirmed cases have also been reported from the Region of the Americas, Eastern Mediterranean Region and Western Pacific Region.
In addition to the cases reported from or identified in non-endemic countries, WHO continues to receive updates on the status of ongoing monkeypox outbreaks in endemic countries in the African region through established surveillance mechanisms (Integrated Disease Surveillance and Response). From January to June 1, 2022, 1408 suspected and 44 confirmed cases including 66 deaths were reported from seven endemic countries.
WHO said it continues to support sharing of information about this outbreak of monkeypox. Clinical and public health incident response has been activated at WHO and in many Member States to coordinate comprehensive case findings, contact tracing, laboratory investigation, clinical management, isolation, and implementation of infection and prevention and control measures.
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Cairo (AP): Iran swiftly reversed course on reopening the Strait of Hormuz, reimposing restrictions on the critical waterway on Saturday after the US said it would not end its blockade of Iran-linked shipping.
Iran's joint military command said on Saturday that “control of the Strait of Hormuz has returned to its previous state ... under strict management and control of the armed forces.” It warned that it would continue to block transit through the strait as long as the US blockade of Iranian ports remained in effect.
The announcement came the morning after US President Donald Trump said that even after Iran announced the strait's reopening on Friday, the American blockade “will remain in full force” until Tehran reaches a deal with the US, including on its nuclear programme.
The conflict over the chokepoint threatened to deepen the energy crisis roiling the global economy after oil prices began to fall again on Friday on hopes the US and Iran were drawing closer to an agreement. Roughly one-fifth of the world's oil passes through the strait, and further limits would squeeze already constrained supply, driving prices higher once again.
Control over the strait has proven to be one of Iran's main points of leverage and prompted the United States to deploy forces and initiate a blockade on Iranian ports as part of an effort to force Iran to accept a Pakistan-brokered ceasefire to end almost seven weeks of war that has raged between Israel, the US and Iran.
Iran said it fully reopened the Strait of Hormuz to commercial vessels after a 10-day truce was announced between Israel and the Iranian-backed Hezbollah militant group in Lebanon. But after Trump said the blockade would continue, top Iranian officials said his announcement violated last week's ceasefire agreement between Iran and the US and warned the strait would not stay open if the US blockade remained in effect.
A data firm, Kpler, said movement through the strait remained confined to corridors requiring Iran's approval.
US forces have sent 21 ships back to Iran since the blockade began on Monday, US Central Command said on X.
Truce in Lebanon could help US-Iran peace efforts
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The ceasefire in Lebanon could clear one major obstacle to an agreement. But it was unclear to what extent Hezbollah would abide by a deal it did not play a role in negotiating, and which will leave Israeli troops occupying a stretch of southern Lebanon.
Trump said in another post that Israel is “prohibited” by the US from further strikes on Lebanon and that “enough is enough” in the Israel-Hezbollah war.
The State Department said the prohibition applies only to offensive attacks and not to actions taken in self-defence.
Shortly before Trump's post, Israeli Prime Minister Benjamin Netanyahu said Israel agreed to the ceasefire in Lebanon “at the request of my friend President Trump,” but that the campaign against Hezbollah is not complete.
He claimed Israel had destroyed about 90 per cent of Hezbollah's missile and rocket stockpiles and added that Israeli forces “have not finished yet” with the dismantling of the group.
In Beirut, displaced families began moving toward southern Lebanon and Beirut's southern suburbs despite warnings by officials not to return to their homes until it became clear whether the ceasefire would hold.
The Lebanese army and UN peacekeepers in southern Lebanon reported sporadic artillery shelling in some parts of southern Lebanon in the hours after the ceasefire took effect.
An end to Israel's war with Hezbollah was a key demand of Iranian negotiators, who previously accused Israel of breaking last week's ceasefire with strikes on Lebanon. Israel had said that the deal did not cover Lebanon.
The fighting has killed at least 3,000 people in Iran, more than 2,290 in Lebanon, 23 in Israel and more than a dozen in Gulf Arab states. Thirteen US service members have also been killed.
