80 per cent COVID-19 immunity lost in 6 months in some after Pfizer shot: US study
Washington, (PT): COVID-19 antibodies produced by the Pfizer vaccine decreased more than 80 per cent in senior nursing home residents and their caregivers six months after receiving their second dose, a US study has found.
The research led by Case Western Reserve University and Brown University in the US studied blood samples of 120 nursing home residents and 92 health care workers.
The researchers particularly looked at humoral immunity -- also called antibody-mediated immunity -- to measure the body's defences against the SARS-CoV-2 virus, which causes COVID-19.
The yet-to-be published study, posted on the preprint server medRxiv, found that individuals' antibody levels decreased more than 80 per cent after six months.
The results were the same in seniors, with a median age of 76, and caregivers, with a median age of 48, and old alike, according to the researchers.
Earlier research by the team found that within two weeks of receiving the second dose of vaccine, seniors who had not previously contracted COVID-19 already showed a reduced response in antibodies that was substantially lower than the younger caregivers experienced.
By six months after vaccination, the blood of 70 per cent of these nursing home residents had "very poor ability to neutralise the coronavirus infection in laboratory experiments," said David Canaday, a professor at the Case Western Reserve University.
The results support the Centers for Disease Control and Prevention's (CDC), recommendation for booster shots especially for the elderly due to fading immunity, Canaday said.
The study noted that the boosters are even more important as the Delta variant spreads.
Early in the pandemic, higher COVID-19 mortality among nursing home residents in the US led to making them a priority for vaccination, the researchers said.
Most nursing home residents received the Pfizer vaccine under the emergency use authorisations because it was the first available vaccine on the market, they said.
"With nursing home residents' poor initial vaccine response, the rise of breakthrough infections and outbreaks, characterisation of the durability of immunity to inform public health policy on the need for boosting is needed," the authors of the study added.
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Four arrested, minor detained for killing teenager in UP's Gorakhpur
Gorakhpur (UP)(PTI) Police on Tuesday arrested four persons and detained a boy in connection with the killing of a teenager at a school here, officials said.
The arrested accused have been identified as Dayanand alias Chhotu, Hrithik Roshan alias Roshan, Uday alias Kishan Kumar and Deepak, all residents of Pipraich police station area here and aged 19-20, the police officials said.
The detained minor will be produced before the Juvenile Justice Board, they said.
Police recovered a country-made pistol and a motorcycle allegedly used by the accused in the commission of the crime, they added.
Superintendent of Police (North) Gyanendra Nath Prasad said the arrests were made following sustained investigation and technical surveillance, and further legal proceedings were underway.
According to police, Sudhir Bharti (17), a class 11 student, was shot dead by the accused on December 26 over old enmity and a dispute triggered by social media posts in the playground of a school in the Pipraich area here.
Based on the complaint filed by Bharti's family, a case was registered under sections 103(1) (punishment for murder) and 61(2) (party to a criminal conspiracy) of the Bharatiya Nyaya Sanhita and relevant provisions of the Arms Act.
According to eyewitnesses, Bharti was in the playground when he had an argument with a person from the same neighbourhood.
The argument escalated and the accused shot him with a country-made pistol, killing him on the spot, they said.
