In an unconventional approach to treating cancer, Croatian virologist Beata Halassy, 49, recently treated her recurrent breast cancer using lab-grown viruses in a procedure known as oncolytic virotherapy (OVT). With the tumour shrinking significantly, Halassy was able to undergo successful surgical removal and has remained cancer-free for four years. This unusual self-treatment has sparked discussions around the ethics of self-experimentation in medicine.
The treatment, detailed in the journal ‘Vaccines’, involved injecting the tumour with viruses she cultivated herself. Halassy used two viruses consecutively – a measles virus and vesicular stomatitis virus (VSV), both known to target her tumour type and previously trialled in other forms of cancer. Over two months, she administered the injections with research-grade material prepared in her lab. Monitoring by her oncologists allowed her to shift to conventional chemotherapy if necessary, though the treatment proceeded without significant side effects. Ultimately, the tumour detached from surrounding tissue, facilitating its surgical removal. Post-surgery analysis confirmed an immune response, with lymphocytes actively infiltrating the tumour.
Although the approach proved effective, Halassy faced challenges in publishing her findings, with journals hesitant over ethical concerns. Jacob Sherkow, a law and medicine researcher, pointed out the ethical risks of promoting self-experimentation, as it may encourage patients to bypass standard treatments. However, Sherkow noted the value of preserving the knowledge gained from such cases.
OVT remains experimental, with some forms approved for metastatic melanoma in the U.S., but no official treatment for breast cancer. Halassy, who is not an oncologist, emphasised that her expertise in virology gave her confidence in attempting the treatment, though she warns others not to view self-treatment as a first option in cancer care.
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Shivamogga: A 17-year-old student from Kamakshi Street in the city, Prem Kumar, died of drowning while swimming in River Tunga in Pillangiri village of the taluk recently.
Prem, who was studying in II PUC at DVS College, was visiting the temple in Pillangiri with his friends and got into the river for a swim, when he drowned in the waters of the river.
The youngster’s body has been sent to the mortuary of the McGann Hospital in Shivamogga to conduct a post-mortem examination.
Shivamogga Rural Police visited the spot and held an inspection.
