Geneva:Health officials in Africa say the rollout of rapid diagnostic tests for COVID-19 could be a game changer for their fight against the coronavirus but also warned Thursday that increased testing could drive up confirmed cases on a continent that has seen them decline or plateauing as case numbers soar in the West.
Some experts worry that Africa so far has lacked the ability to test widely enough, especially in hard-to-reach rural areas, and that its case counts therefore don't reflect reality and impede tracking the virus.
African countries are gearing up to introduce antigen-based rapid diagnostic tests on a large scale, and this will be a game changer, we think, in the fight against COVID-19, Dr. Matshidiso Moeti, the World Health Organisation's regional director for Africa, said.
These high-quality rapid tests will help meet the huge unmet need for testing in Africa. Speaking from Brazzaville, Congo, at an online news conference, Moeti noted that WHO Africa region comprising sub-Saharan Africa plus Algeria - has seen a downward trend from a daily average of more than 15,000 cases in July to less than 4,000 in the past month - prompting some governments to pull back from their toughest containment measures.
As countries ease restrictions on movement, some increase in cases is expected, but preventing an exponential rise is absolutely critical, she said.
From early on in the pandemic, officials at WHO headquarters in Geneva, including the U.N. health agency's Ethiopian director-general, Tedros Adhanom Ghebreyesus, have expressed concerns that COVID-19 could have a big impact on weaker health systems like those in Africa.
However, developed countries with world-class health systems so far have been among the ones hardest hit by virus outbreaks. WHO's 54-nation European region tallied 927,000 cases in its latest weekly count, a new record high.
Dr Susan Ndidde Nabadda, head of the Ugandan National Health Laboratory Services and Central Public Health Laboratory, suggested that it could take some time to ensure proper authorizations and a high-quality process before rapid diagnostic tests on a broader scale because there is no longer really a lot of emergency in Africa.
Nabadda cited reports indicating that the identification of COVID-19 cases increased in Guinea once the west African country started rolling out the RDTs, noting that we might see more numbers coming on board as the tests are deployed more widely.
She said the relative lack of testing in Africa could be one of the reasons why African case counts were lower than in developed countries.
WHO announced last month that it and leading partners have agreed on a plan to roll out 120 million rapid diagnostic tests for COVID-19 to help lower- and middle-income countries make up ground in a testing gap with richer countries.
The antigen-based rapid diagnostic tests for which WHO issued an emergency use listing are intended to provide better testing access to areas where it is harder to distribute the PCR tests often in many wealthier nations.
The rapid tests look for antigens, or proteins found on the surface of the virus. They are generally considered less accurate though much faster than PCRs, which are higher-grade genetic tests. PCR tests require processing with specialty lab equipment and chemicals. Typically, delivering results to patients takes several days.
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Mumbai: Ikkis, the latest war drama directed by Sriram Raghavan, has delivered a stronger-than-expected opening at the box office, earning an estimated ₹7 crore net in India on its first day, Hindustan Times reported on Friday.
The film, starring Agastya Nanda, opened in theatres on January 1 across nearly 4,000 screens nationwide. Trade analysts had earlier projected a modest opening of ₹2–2.5 crore, especially given stiff competition from Dhurandhar, which continues to perform strongly at the box office.
Despite these expectations, Ikkis exceeded projections by nearly three times, helped largely by positive word of mouth. As per the report, the film had around 12% occupancy in the morning shows across the country, which jumped to 35% by afternoon, and 47% in the evening, indicating growing audience interest as the day progressed.
While Dhurandhar dominated the day with a reported ₹15 crore collection, trade observers note that Ikkis holding its ground amid such competition is a promising sign, particularly for its performance over the extended opening weekend.
Ikkis is based on the life of Arun Khetarpal, the youngest recipient of India’s highest gallantry award, the Param Vir Chakra. The film chronicles Khetarpal’s exploits and bravery during the 1971 India-Pakistan War. Agastya plays Khetarpal in the film.
While screen legend Dharmendra appears as his father in his final performance, Dharmendra died a little over a month before the film’s release. Ikkis is also among the final films of the late Asrani, who also died late last year. The film also stars Jaideep Ahlawat and Deepak Dobriyal.
