AIIMS Panel Gives Nod To Human Clinical Trial Of Anti-COVID-19 Vaccine
New Delhi: The AIIMS Ethics Committee on Saturday gave its nod for a human clinical trial of the indigenously developed COVID-19 vaccine candidate Covaxin following which the premier hospital is likely to begin the exercise by enrolling healthy volunteers from Monday.
AIIMS-Delhi is among the 12 sites selected by the Indian Council for Medical Research (ICMR) for conducting phase I and II human trials of Covaxin. In phase I, the vaccine would be tested on 375 volunteers and a maximum of 100 of them would be from AIIMS.
"The AIIMS Ethics Committee gave its approval for starting the human clinical trial of the indigenously developed Covaxin today. Healthy volunteers having no comorbid conditions and without a history of COVID-19, aged more than 18 years and less than 55 years, would be eligible to participate in the randomised, double-blind, placebo-controlled clinical trial," Dr Sanjay Rai, Professor at the Centre for Community Medicine at AIIMS said.
"Few volunteers have already registered for the trial. We would start the screening of the individuals and evaluate their health condition from Monday onwards before vaccinating them," Rai, who is also the principal investigator of the study, said.
Anybody willing to participate in the trial can send an email to Ctaiims.covid19@gmail.com or an SMS to or call on 7428847499, he said. The institute may also put up these contact details on its website.
According to Rai, the Ethics Committee had raised few concerns in the protocol submitted for carrying out of the trial.
"Those concerns were addressed to the following which the EC gave its approval to begin the trial by the premier institute," he said.
COVID-19 vaccine candidate Covaxin, developed by the Hyderabad-based Bharat Biotech in collaboration with the ICMR and the National Institute of Virology (NIV), had recently got the nod for human clinical trials from the Drugs Controller General of India (DCGI).
Noting that this was the first indigenous vaccine being developed by India, ICMR Director-General Dr. Balram Bhargava in a letter to principal investigators of the 12 sites recently had asked them to fast-track the human clinical trial approvals stating it is one of the "top priority projects which is being monitored at the top-most level of the government".
The trials have so far started in AIIMS, Patna, and some more sites.
The DCGI has permitted two vaccines -- one developed by the Bharat Biotech International Limited in collaboration with the ICMR and another one by Zydas Cadila Healthcare Ltd to go in for phase I and II human clinical trials.
Dr. Balram Bhargava had said these two vaccine candidates have undergone successful toxicity studies in rats, mice, and rabbits, and these data was submitted to DCGI following which both got clearance to start the early phase human trials early this month.
They have got their sites ready and approximately 1,000 human volunteers would be participating in the exercise for each of the two indigenously developed vaccine candidates, he had said.
Since India is one of the largest vaccine producers in the world, it is the country's "moral responsibility" to fast-track the vaccine development process to break the chain of coronavirus transmission, he had said.
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Karnataka rolls out climate action plan to tackle global warming: Minister Khandre
Bengaluru (PTI): Minister Eshwar Khandre on Tuesday said that a Karnataka state action plan on climate change has been formulated to mitigate the impact of global warming and climate change, and directions have been issued to ensure its proper implementation.
Speaking after presiding over a seminar on extreme heat and its impact on Bengaluru, organised by the Karnataka Media Academy, he said the Environmental Management and Policy Research Institute (EMPRI), which comes under the environment department, has taken steps to implement the action plan in coordination with various state government departments.
He said training programmes are being organised in cooperation with zilla panchayat offices for district officials and other related institutions regarding the implementation and progress of the Karnataka state action plan on climate change.
The Forest, Ecology and Environment minister said such programmes will be conducted in all 31 districts of Karnataka.
According to a statement issued by the minister’s office, in terms of climate resilience, Khandre said a dedicated radio programme, “Havamaana Mitra” (weather friend), was launched in April 2025 to share information on best practices, and 24 programmes have so far been broadcast on Akashvani.
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He said these efforts aim to create public awareness.
Khandre emphasised that due to global warming and climate change, even seasons are changing today.
“Keeping this in mind, after becoming Forest Minister, I have been making every effort to increase green cover, especially in Bengaluru city,” he said.
He noted that during the last three years, about 11 crore saplings have been planted in the state, and information on their survival rate has been made available on the Forest Department website.
According to him, encroachments on about 250 acres of forest land worth around Rs 10,000 crore in several parts of Bengaluru, including Kothanur, Kadugodi, B M Kaval, and Turahalli, have been cleared.
Thousands of saplings have been planted and groves created on the cleared land, thereby preserving lung spaces essential for Bengaluru city.
The minister also recalled that more than 400 acres of forest land in Peenya plantation had earlier been allotted to the central government-owned HMT for industrial purposes.
He said HMT had sold 160 acres of this land, while 280 acres remain, and a decision has been taken to reclaim it for the department to preserve an essential lung space for Bengaluru. A legal battle is underway, and the case is currently in the Supreme Court.
In addition, he said 444 acres in the Jarakabande area had been allotted to the Indian Air Force. Under the Forest (Conservation) Act, 1980, forest land cannot be diverted without due process. Hence, in 2017, the then Deputy Commissioner cancelled the land allotment.
“Steps are now being taken to reclaim this forest land and preserve the green space,” he said.
Khandre also highlighted that the Yelahanka Air Force Station in Gantiganahalli, where the international air show is held once every two years in Bengaluru, is on forest land.
He said 159 acres in Gantiganahalli village is classified as a reserved forest area.
“If the Air Force submits a proposal for diversion and provides alternative land, this area may be considered for transfer; otherwise, steps will be taken to reclaim it for the forest department,” he said.
“The Indian Air Force is presently using this area as a runway. However, the RTC and mutation records are in the name of the Forest Department, and the land has not been legally converted. Hence, this forest land will be reclaimed,” he said.
He added that the government has resolved to construct a major biological park on 153 acres at Madappanahalli in Bengaluru North taluk, and cabinet approval has been obtained.
“The CM will lay the foundation stone next month. This will be the largest park after Lalbagh and Cubbon Park. It would not be incorrect to call this an achievement of the century,” he said.
