New Delhi, Aug 22: The government has banned 156 widely sold fixed-dose combination (FDC) drugs including antibacterial medicines used for fever, cold, allergies and pain, saying that they are "likely to involve risk to human beings".
FDC drugs are those which contain a combination of two or more active pharmaceutical ingredients in a fixed ratio and are also referred to as "cocktail" drugs.
According to a gazette notification issued by the Union health ministry on August 12, the government has banned 'Aceclofenac 50mg + Paracetamol 125mg tablet', one of the popular combinations used as pain-relieving medicines manufactured by top pharma companies.
The list also includes Mefenamic Acid + Paracetamol Injection, Cetirizine HCl + Paracetamol + Phenylephrine HCl, Levocetirizine + Phenylephrine HCl + Paracetamol, Paracetamol + Chlorpheniramine Maleate + Phenyl Propanolamine and Camylofin Dihydrochloride 25 mg + Paracetamol 300mg.
The Centre also banned the combination of Paracetamol, Tramadol, Taurine and Caffeine. Tramadol is an opioid-based pain killer.
"The Central government is satisfied that the use of the Fixed Dose Combination drug is likely to involve risk to human beings whereas safer alternatives to the said drug are available," the notification said.
It said that the matter was examined by an Expert Committee appointed by the Centre which considered these FDCs as "irrational".
It further stated that the apex panel Drugs Technical Advisory Board (DTAB) also examined these FDCs and recommended that "there is no therapeutic justification for the ingredients contained in these FDCs".
"The FDC may involve risk to human beings. Hence in the larger public interest, it is necessary to prohibit the manufacture, sale or distribution of this FDC under section 26 A of Drugs and Cosmetics Act 1940," the notification read.
"In view of above, any kind of regulation or restriction to allow for any use in patients is not justifiable. Therefore, only prohibition under section 26A is recommended," it added.
Following the DTAB's recommendations, the notification said that "the Central government is satisfied that it is necessary and expedient in public interest to prohibit the manufacture, sale and distribution for human use of the said drug in the country".
The list includes certain products which were already discontinued by many drug makers.
The government in 2016 had announced the ban on the manufacture, sale and distribution of 344 drug combinations after an expert panel, set up at the behest of the Supreme Court, had stated they were being sold to patients without scientific data and the order was challenged by the manufacturers in court, sources said.
In June 2023, 14 FDCs which were part of those 344 drug combinations, were banned. Many of the FDCs banned recently were also from those 344 drug combinations, the sources said.
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Bhubaneswar (PTI): In the fourth such incident within a month, a 13-year-old girl allegedly set herself on fire and is struggling for life at a hospital in Odisha’s Bargarh district, police said on Monday.
The incident took place at Phiringmal village within Gaisilat police station limits.
The minor was rescued by villagers from a football ground in a half-burnt condition and rushed to Bargarh district headquarters hospital, where her condition is stated to be critical, police said.
"The reason behind the self-immolation is not yet known. The victim, a class 8 student, used petrol to set herself on fire," police added.
The latest incident follows the deaths of three other women by burning since July 12.
On that day, a 20-year-old woman student in Balasore set herself ablaze on her college campus and died at AIIMS Bhubaneswar on July 14.
On July 19, a minor girl was allegedly set on fire by three miscreants in Balanga and died at AIIMS Delhi on August 2.
The third such incident took place in Kendrapara district on August 6, when a third-year undergraduate woman college student’s charred body was found from her house under Pattamundai (rural) police station area.