Final analysis of Covaxin efficacy out; vaccine 65.2 percent effective against Delta variant
Hyderabad: Bharat Biotech's Covaxin has demonstrated 77.8 per cent effectiveness against symptomatic COVID-19 and65.2 per cent protection against the new Delta variant.
The company on Saturday said it concluded the final analysis of Covaxin efficacy from Phase3 trials.
The efficacy analysis demonstrates Covaxin to be 93.4 per cent effective against severe symptomatic COVID-19 cases while safety analysis shows adverse events reported were similar to placebo, with 12 per cent of subjects experiencing commonly known side effects and less than 0.5 per cent feeling serious adverse events.
The efficacy data demonstrates 63.6 per cent protection against asymptomatic COVID-19, a release from the city-based vaccine maker said.
Phase 3 clinical trials of the vaccine was an event driven analysis of 130 symptomatic COVID-19 cases, reported at least two weeks after the second dose, conducted at 25 sites across India.
The whole virion inactivated vaccine against SARS-CoV2, was developed in partnership with Indian Council of Medical Research and National Institute ofVirology in Pune.
Krishna Ella, Chairman and Managing Director of Bharat Biotech, said, "The successful safety and efficacy readouts of Covaxin as a result of conducting the largest ever COVID Vaccines trials in India establishes the ability of India and developing world countries to focus towards innovation and novel product development.
We are proud to state that Innovation from India will now be available to protect global populations."
Director General of ICMR, Balram Bhargava said, "I am delighted to note that Covaxin developed by ICMR and BBIL under an effective public private partnership, has demonstrated an overall efficacy of 77.8 per cent in India's largest COVID phase 3 clinical trial thus far.
Our scientists at ICMR and BBIL have worked tirelessly to deliver a truly effective vaccine of highest international standards."
He further said Covaxin will not only benefit the Indian citizens but would also immensely contribute to protect the global community against the deadly SARS-CoV-2 virus.
"I am also pleased to see that Covaxin works well against all variant strains of SARS-CoV-2.
The successful development of Covaxin has consolidated the position of Indian academia and Industry in the global arena," Bhargava said.
The Phase 3 trials were conducted between November 16, 2020 and January 7, 2021 with 25,798 participants who were randomised to BBV152 or placebo groups.
The preprint data of COVAXIN efficacy has not been certified by peer-review, according to Medrxiv in which thedata was published.
Let the Truth be known. If you read VB and like VB, please be a VB Supporter and Help us deliver the Truth to one and all.
Mangaluru’s Karavali Utsava is back; Cultural, beach events lined up, here’s the complete schedule
Mangaluru: This year’s Karavali Utsava will commence on December 20, with a wide range of cultural, adventure, and tourism-focused programs planned across Mangaluru and other parts of the Dakshina Kannada district, Deputy Commissioner Darshan H.V. said.
He was speaking while presiding over a Karavali Utsava preparedness review meeting held at the District Commissioner’s office.
The main event will be held at the Karavali Utsava grounds in the city. In an effort to promote beach tourism, special programs will be organised at six beaches across the district, which include Panambur, Ullal, Someshwara, Sasihitlu, Tannirbhavi, and the Blue Flag Beach.
ALSO READ: Udupi: Toddler slips from mother's hand while drawing water from well, dies
Outlining the schedule, the Deputy Commissioner said adventure sports will be held at Sasihitlu Beach, while a wine, cheese, and cake festival will take place at the Tannirbhavi Blue Flag Beach.
A music festival and triathlon are planned at Tannirbhavi Beach. Football, volleyball and other sports events will be organised at Ullal Beach, cultural programs at Panambur Beach, and a music evening and yoga program at Someshwara Beach.
In addition, food festivals featuring a variety of local and regional cuisines will be held at all beaches. The Kala Parba program and a flower and floriculture exhibition will be organised at Kadri Park, while a film festival is also planned in Mangaluru city.
A football tournament will be held at Nehru Maidan on December 27 and 28, and special programs will be organised at Pilikula Nisargadhama. To attract tourists, helicopter joyrides have also been arranged, the Deputy Commissioner said.
The review meeting was attended by Zilla Panchayat Chief Executive Officer Narvade Vinayak Karbari, Mangaluru Deputy Divisional Officer Meenakshi Arya, Deputy Commissioner of Police Mithun H.N., Deputy Conservator of Forests Antony Mariappa, and other officials.
