New coronavirus variant 'IHU' identified in France
New Delhi, Jan 4: As the world grapples with the highly mutated Omicron variant of SARS-CoV-2, scientists have identified a new strain of the COVID-19 causing virus in Southern France.
Known as 'IHU', the B.1.640.2 variant has been reported by researchers at institute IHU Mediterranee Infection in at least 12 cases, and has been linked to travel to African country Cameroon.
However, the researchers noted that it is too early to speculate on how this variant behaves as far as infection and protection from vaccines is concerned.
The yet-to-be peer-reviewed study, posted on the preprint repository MedRxiv on December 29, revealed that IHU has 46 mutations and 37 deletions resulting in 30 amino acid substitutions and 12 deletions.
Amino acids are molecules that combine to form proteins, and both are the building blocks of life.
Fourteen amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein.
Most currently used vaccines are targeted at the spike protein of SARS-CoV-2, which the virus uses to enter and infect the cells.
N501Y and E484K mutations were earlier also found in Beta, Gamma, Theta and Omicron variants.
"The mutation set and phylogenetic position of the genomes obtained here indicate based on our previous definition a new variant we named IHU," the authors of the study said.
"These data are another example of the unpredictability of the emergence of SARS-CoV-2 variants, and of their introduction in a given geographical area from abroad," they added.
The B.1.640.2 has not been identified in other countries so far or labelled a variant under investigation by the World Health Organization (WHO).
According to the researchers, the index (first) case was an adult diagnosed positive by RTPCR performed in a laboratory on a nasopharyngeal sample collected in mid-November last year.
Epidemiologist Eric Feigl-Ding posted a long Twitter thread in which he said that new variants keep emerging but it does not necessarily mean they will be more dangerous.
"What makes a variant more well-known and dangerous is its ability to multiply because of the number of mutations it has in relation to the original virus," Feigl-Ding tweeted on Tuesday.
"This is when it becomes a "variant of concern" - like Omicron, which is more contagious and more past immunity evasive. It remains to be seen in which category this new variant will fall," he said.
Many countries are currently experiencing a spike in COVID-19 cases driven by the Omicron variant which was first identified in South Africa and Botswana in November last year.
Since then, the variant of concern has spread to over 100 countries.
In India, a total of 1,892 cases of Omicron variant have been detected across 23 states and Union Territories so far.
Let the Truth be known. If you read VB and like VB, please be a VB Supporter and Help us deliver the Truth to one and all.
Real Madrid fines Valverde and Tchouaméni half a million euros each for altercation
Barcelona (AP): Real Madrid slapped players Federico Valverde and Aurélien Tchouaméni with half-a-million-euro ($588,000) fines on Friday for their altercation during practice.
The massive fines came a day after the midfielders tussled when the team trained. Valverde said in a post on social media on Thursday that no punches were thrown. But Valverde knocked his head on a table and he suffered a small cut that required a brief hospital visit.
On social media, Valverde initially called it a “meaningless fight” with a teammate and said “everything has been blown out of proportion."
His employers, however, considered it a significant enough breach of team discipline to nail both Valverde and Tchouaméni with fines that bite even the bank account of a top soccer player. The half-a-million euro penalties reflect the reputational damage the club was enduring in a chaotic end to a disappointing season.
In a statement, the 15-time European champion said its disciplinary action was concluded after both players expressed to the club “their complete remorse for what happened and apologized to one another.”
Madrid added they also apologized to their teammates, the coaching staff and club supporters, as well as showing their willingness to accept whatever disciplinary action the club deemed “opportune.”
Tchouaméni was back training with Madrid on Friday, two days before they play at Barcelona in a clasico. Madrid has to win otherwise Barcelona will be crowned La Liga champion.
After being notified of the fine, he posted a public apology to the club and its fans on social media.
“What happened this week in training is unacceptable,” Tchouaméni wrote. "I say this while thinking about the example we are expected to set for young people, whether in football or at school.
“Above all, I am sorry for the image we projected of the club.”
Valverde was not at practice due to the head knock.
Both players are set to play in the World Cup next month, with Tchouaméni playing for France and Valverde for Uruguay.
Chaotic end to a poor season
===================
The run-in between the players, who for seasons have played side by side in Madrid's midfield, came after they argued this week in previous training sessions. But tempers boiled over on Thursday. Spanish media was rife with reports that the players previously disagreed over the club's decision to let coach Xabi Alonso go after just months on the job.
It was not the only altercation involving Madrid players during training this week. Álvaro Carreras confirmed he was in a “minor” incident with a teammate. Spanish media said he and fellow defender Antonio Rüdiger got into a scuffle.
Álvaro Arbeloa, the coach who was promoted from Madrid's reserve team when Alonso was fired in January, will face tough questions on what went wrong inside the changing room when he gives a press conference on Saturday ahead of the clasico at Camp Nou.
Madrid is facing a second consecutive campaign without a major trophy amid rumors in the Spanish media that club president Florentino Pérez is considering bringing back Jose Mourinho to straighten out his underperforming team.
