New study reveals adverse events in some covaxin recipients
New Delhi: A recent study conducted by Sankha Shubhra Chakrabarti and his team at Banaras Hindu University has shed light on adverse events observed in participants who received Covaxin, Bharat Biotech's COVID-19 vaccine.
The study involved 1,024 individuals, comprising 635 adolescents and 291 adults, who were followed up for one year after receiving Covaxin.
Nearly a third of the participants reported adverse events of special interest (AESI) during the observation period. These included viral upper respiratory tract infections, new-onset skin and subcutaneous disorders, general disorders, nervous system disorders, menstrual abnormalities in females, ocular abnormalities, and hypothyroidism.
The study identified several risk factors associated with AESI. Female adolescents and individuals with a history of allergies were found to be at higher risk. Additionally, participants with pre-vaccination COVID-19, comorbidities, and post-vaccination typhoid were also identified as having increased risk.
A significant number of AESIs persisted even at the 1-year follow-up. Female individuals, adolescents with pre-vaccination COVID-19, those with comorbidities, and those with post-vaccination typhoid had higher odds of persistent AESIs.
Among serious adverse events, stroke and Guillain-Barre Syndrome were identified in a small percentage of participants.
The study highlights the importance of extended surveillance of COVID-19 vaccinated individuals to understand the course and outcomes of late-onset adverse events. Focused monitoring for persistent AESIs is recommended, especially for individuals with certain risk factors.
The findings suggest that the patterns of adverse events observed with Covaxin differ from those reported with other COVID-19 vaccines. Understanding these patterns is crucial for effective post-vaccination monitoring and management of potential risks.
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Rickelton's ton in vain as SRH beat MI by 6 wickets
Mumbai (PTI): Ryan Rickelton's whirlwind unbeaten ton was overshadowed by Heinrich Klaasen's unbeaten 65 as Sunrisers Hyderabad defeated Mumbai Indians by six wickets in an IPL match here on Wednesday.
Chasing an imposing 244-run target, Travis Head (76 off 30) and Abhishek Sharma (45 off 24) shared 129 runs for the opening wicket to set the platform for SRH.
Klaasen (65 not out off 30 balls) then displayed his all-round hitting abilities to guide SRH home with the help of Nitish Kumar Reddy (21) and Salil Arora (30 not out off 10) in 18.4 overs.
Earlier, Rickelton's knock powered MI to 243 for five.
MI rode on a 93-run stand between Rickelton (123 not out off 55 balls) and Will Jacks (46 off 22) in 7.1 overs for the opening stand to power the side.
MI skipper Hardik Pandya scored a valuable 31 off 15 balls before being dismissed.
Praful Hinge (2/54), Eshan Malinga (1/29), Sakib Hasan (1/39) and Nitish Kumar Reddy (1/31) were the wicket-takers for SRH.
Brief Scores:
Mumbai Indian: 243 for 5 in 20 overs (Ryan Rickelton 123 not out; Praful Hinge 2/54).
Sunrisers Hyderabad: 249 for 4 in 18.4 overs (Travis Head 76, Heinrich Klaasen 65 not out; AM Ghazanfar 2/51).
