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New Delhi: Bharat Biotech that is developing the coronavirus vaccine COVAXIN in its latest report has said an animal study has shown a vaccine candidate has helped develop a strong immune response to the highly infectious coronavirus.

"To summarise, the vaccine candidate was found to generate robust immune responses. Thus, preventing infection and disease in the primates upon high amounts of exposure to live SARS-CoV-2 virus," Bharat Biotech posted on its website.

"These results demonstrate the protective efficacy in a live viral challenge model," the company tweeted.

It said 20 rhesus macaques divided into four groups were given the vaccine candidate.

"One group was administered with placebo, while three groups were immunised with three different vaccine candidates at zero and 14 days. All the macaques were exposed to viral challenge 14 days after the second dose," Bharat Biotech said.

"The results showed protective efficacy, increasing SARS-CoV-2 specific IgG and neutralising antibodies, reducing replication of the virus in the nasal cavity, throat, and lung tissues of monkey. No evidence of pneumonia was observed by histopathological examination in vaccinated groups, unlike the placebo group. Adverse events were not seen in animals immunised with a two-dose vaccination regimen," Bharat Biotech said.
 
 

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Vijayanagara: One man was killed and 12 others were injured after a truck hit vehicle they were traveling in on the National Highway 50 stretch on the outskirts of Koodligi in the district.

The accident victim, Madhu (27), is learned to have been an employee of Reliance Digital from Andhra Pradesh.

The vehicle was reportedly traveling from Bengaluru to Koodligi and the passengers are learned to have been seriously injured following the collision with the truck, which was found to have a Maharashtra registration.

Koodligi Deputy Superintendent of Police (DySP) Mallesh Dodmani and Circle Inspector Prahlad Channagiri arrived at the accident spot on being informed of the accident.

The police officers and locals rescued the injured passengers and got them shifted to the Koodligi Government Hospital. Some of the passengers were reportedly taken to the Ballari Trauma Care Centre for further treatment.

A case has been registered at the Koodligi Police Station and the officers are investigating the incident.

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