London (PTI): Exposure to traffic related air pollution is associated with an increased risk of multiple long-term physical and mental health conditions, according to a study.
This is the largest study worldwide -- conducted on over 364,000 (over 3.6 lakh) people in England -- to examine whether air pollution exposure is linked with the occurrence of multiple long-term health conditions, the researchers said.
The study, published in the journal Frontiers in Public Health, showed that high levels of traffic-related air pollution - fine particulate matter (PM2.5) and nitrogen dioxide (NO2) were associated with an increased risk of having at least two long term health conditions.
The strongest associations were observed for co-occurring neurological, respiratory, cardiovascular and common mental health conditions such as depression and anxiety, the researchers said.
"People with more than one long-term health condition have a lower quality of life and greater dependence on the healthcare system," said Amy Ronaldson, Research Associate at King's College London and first author on the study.
"Our research has indicated that those people that live in areas of higher traffic-related air pollution are at greater risk of having multiple health conditions," Ronaldson said.
However, the study does not prove that air pollution causes multimorbidity, but it does warrant further research in this area, the researchers said.
They analysed data from UK Biobank - a large-scale biomedical database and research resource containing anonymised genetic, lifestyle and health information from half a million UK participants aged between 40 and 69 years.
Participants were assessed for 36 physical and five mental health chronic conditions. Multimorbidity was defined as having two or more of these conditions.
Physical and mental health data from UK Biobank in 2010 were linked with the estimated concentration of air pollution at the residential address of the participants.
The study found that those participants exposed to higher concentrations above 10 microgramme per cubic metre ( g/m3) of fine particulate matter had a 21 per cent increased risk of two or more co-occurring conditions compared to those exposed to concentrations below 10 g/m3.
For participants exposed to above 30 g/m3 of NO2, the study showed a 20 per cent increased risk of having two or more co-occurring conditions compared to those participants that were exposed to concentrations of NO2 below 20 g/m3.
Amongst those with multiple conditions, increased exposure to both PM2.5 and NO2 was linked to a greater severity of the co-occurring conditions, the researchers said.
"How air pollution affects multiple organs and systems at the same time is not yet fully understood, but there is some evidence that mechanisms such as inflammation, oxidative stress and immune activation could be triggered by air particulates, which can cause damage to the brain, heart, blood, lungs and gut," said Ioannis Bakolis from King's College London.
"Our study suggests that it could be through shared mechanisms that air pollution negatively impacts several body systems and increases the likelihood of people developing multiple long term health conditions," said Bakolis, senior author on the study.
Researchers identified several patterns in the associations. The strongest links were primarily between conditions relating to the respiratory system such as asthma and chronic obstructive pulmonary disease as well as the cardiovascular system like atrial fibrillation, coronary heart disease, and heart failure.
The link was also seen with neurological and common mental conditions such as stroke, substance abuse, depression and anxiety, the researchers added.
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Bengaluru (PTI): The Karnataka government on Monday gave formal approval to the Karnataka State Cricket Association (KSCA)and Royal Challengers Bengaluru (RCB) to host the 2026 Indian Premier League matches at the M. Chinnaswamy Stadium, ending months of uncertainty following the stampede after the team's maiden title win.
The 19th edition of the world's biggest T20 league begins on March 28 with defending champions Royal Challengers Bengaluru set to face Sunrisers Hyderabad in their first match here at the M Chinnaswamy Stadium in the tournament opener, as per the schedule.
The formal approval comes after a meeting chaired by Karnataka home minister Parameshwar with the Expert Committee, which was constituted by the state government, and representatives from the KSCA, RCB and their event management firm DNA.
"During the meeting, the Expert Committee presented its report outlining the preparedness and compliance measures undertaken at the M. Chinnaswamy Stadium," KSCA's official spokesperson Vinay Mruthyunjaya informed in a statement.
"Based on the recommendations of the Expert Committee and after reviewing the arrangements in detail, the Hon’ble Home Minister has formally accorded approval for the conduct of the upcoming IPL matches at the iconic M. Chinnaswamy Stadium, Bengaluru."
"The Karnataka State Cricket Association (KSCA) places on record its sincere gratitude to the Hon’ble Home Minister, Dr. G. Parameshwar, for his leadership, guidance and support in facilitating this approval," he added.
Apart from the opening fixture of the upcoming season , the M Chinnaswamy Stadium is also slated to host the RCB Unboxing event as well as the tournament's opening ceremony.
RCB had earlier announced that it would play five of their seven home matches in Bengaluru, while two will be played at Raipur's Shaheed Veer Narayan Singh International Cricket Stadium.
The KSCA also expressed its gratitude towards the members of the Expert Committee.
"Our special thanks are also due to Shri Sreemant Kumar Singh, Member Secretary of the Expert Committee and Commissioner of Police, Bengaluru, for his proactive coordination and for ensuring that all safety, security and operational aspects were comprehensively evaluated,” the release said.
"KSCA further expresses its sincere appreciation to all the distinguished members of the Expert Committee and the officials associated with the Expert Committee and its sub-committees, whose careful assessment and constructive recommendations have been instrumental in enabling this important decision."
