London (PTI): Exposure to traffic related air pollution is associated with an increased risk of multiple long-term physical and mental health conditions, according to a study.
This is the largest study worldwide -- conducted on over 364,000 (over 3.6 lakh) people in England -- to examine whether air pollution exposure is linked with the occurrence of multiple long-term health conditions, the researchers said.
The study, published in the journal Frontiers in Public Health, showed that high levels of traffic-related air pollution - fine particulate matter (PM2.5) and nitrogen dioxide (NO2) were associated with an increased risk of having at least two long term health conditions.
The strongest associations were observed for co-occurring neurological, respiratory, cardiovascular and common mental health conditions such as depression and anxiety, the researchers said.
"People with more than one long-term health condition have a lower quality of life and greater dependence on the healthcare system," said Amy Ronaldson, Research Associate at King's College London and first author on the study.
"Our research has indicated that those people that live in areas of higher traffic-related air pollution are at greater risk of having multiple health conditions," Ronaldson said.
However, the study does not prove that air pollution causes multimorbidity, but it does warrant further research in this area, the researchers said.
They analysed data from UK Biobank - a large-scale biomedical database and research resource containing anonymised genetic, lifestyle and health information from half a million UK participants aged between 40 and 69 years.
Participants were assessed for 36 physical and five mental health chronic conditions. Multimorbidity was defined as having two or more of these conditions.
Physical and mental health data from UK Biobank in 2010 were linked with the estimated concentration of air pollution at the residential address of the participants.
The study found that those participants exposed to higher concentrations above 10 microgramme per cubic metre ( g/m3) of fine particulate matter had a 21 per cent increased risk of two or more co-occurring conditions compared to those exposed to concentrations below 10 g/m3.
For participants exposed to above 30 g/m3 of NO2, the study showed a 20 per cent increased risk of having two or more co-occurring conditions compared to those participants that were exposed to concentrations of NO2 below 20 g/m3.
Amongst those with multiple conditions, increased exposure to both PM2.5 and NO2 was linked to a greater severity of the co-occurring conditions, the researchers said.
"How air pollution affects multiple organs and systems at the same time is not yet fully understood, but there is some evidence that mechanisms such as inflammation, oxidative stress and immune activation could be triggered by air particulates, which can cause damage to the brain, heart, blood, lungs and gut," said Ioannis Bakolis from King's College London.
"Our study suggests that it could be through shared mechanisms that air pollution negatively impacts several body systems and increases the likelihood of people developing multiple long term health conditions," said Bakolis, senior author on the study.
Researchers identified several patterns in the associations. The strongest links were primarily between conditions relating to the respiratory system such as asthma and chronic obstructive pulmonary disease as well as the cardiovascular system like atrial fibrillation, coronary heart disease, and heart failure.
The link was also seen with neurological and common mental conditions such as stroke, substance abuse, depression and anxiety, the researchers added.
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Pune (PTI): Hundreds of people blocked the Mumbai-Bengaluru highway in Pune to protest the rape and murder of a four-year-old girl, leading to traffic disruption on the busy route for about four hours.
The girl's family members and other demonstrators placed the body on the road in the Navale Bridge area on Saturday evening and demanded stringent punishment for the 65-year-old man arrested in the case.
Several videos surfaced showing a huge traffic jam on the highway.
Later, the victim's last rites were performed at the Vaikunt crematorium here shortly after midnight amid tight police security.
The accused man, who works as a labourer and has a criminal record, allegedly lured the girl with the promise of food on Friday in the Bhor tehsil of Pune district. He then took her to a cattle enclosure where he allegedly sexually assaulted her and later killed her by hitting her with a stone, according to the police.
He was arrested based on CCTV footage from a private residence, which captured him with the child.
A case was registered against him under the relevant provisions of the Bharatiya Nyaya Sanhita and the Protection of Children from Sexual Offences (POCSO) Act and he has been remanded in police custody till May 7.
Maharashtra Deputy Chief Minister Sunetra Pawar on Saturday met the family of the victim, assuring them of strict action against the accused and a fast-track trial.
Describing the incident as "shocking" and a "blot on humanity", Pawar said the government stands firmly with the victim's family and will ensure justice.
She also spoke to Chief Minister Devendra Fadnavis and sought a fast-track court trial so that the accused receives the harshest punishment.
Deputy CM Eknath Shinde directed Pune rural police to gather concrete evidence to build a watertight case and conduct the trial in a fast-track court.
Efforts should be made to ensure the accused gets the death penalty, a statement quoted Shinde as saying.
