New York, April 22: Researchers have found that activity in decision-making brain regions of people who use recreational stimulants can predict who will discontinue their use and who will develop a drug use disorder.
The findings of the study, led by Martin Paulus of Laureate Institute of Brain Research in Oklahoma, suggested that an inability to learn from previous risky decisions in some people may predispose them to continue drug use despite the negative consequences.
"Our sample of recreational users offers a unique approach to studying addiction," said first author Melanie Blair, a doctoral student in the laboratory of Jennifer Stewart of City University of New York.
"By finding differences between our groups prior to problematic use, our results suggest that certain brain patterns might be existing vulnerabilities that predispose an individual to addiction," Blair added.
For the study, published in the journal Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, researchers used brain imaging to measure the activity of several brain regions involved in decision making in 144 young adults.
The study measured brain activity in young adults using recreational stimulants, including cocaine and the prescription amphetamines Adderall and Ritalin, and followed up three years later to determine the participants' outcome.
During the brain scans, the participants performed a task requiring them to make risky or safe decisions. Although all participants in the study were experimenting with stimulants at the time, some showed a tendency for making riskier choices.
"Compared to individuals who stopped using, those who later developed problem use were more reactive to rewards and showed weaker activity in regions of the brain that are critical for decision making," Blair said.
These participants had lower activity in a brain circuit that provides feedback on risky decisions, suggesting they might not be as good at adapting their behaviour-based on previous experiences, the researcher added.
Weaker brain activity in regions associated with decision making also predicted greater marijuana use in the future, they noted.
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Assam to lift all cases against Koch Rajbongshis in Foreigners' Tribunals: CM Himanta Biswa Sarma
Guwahati, Apr 4 (PTI): The Assam cabinet has decided to lift all cases pending against people from the Koch Rajbongshi community in the Foreigners' Tribunals, Chief Minister Himanta Biswa Sarma said on Friday.
They will also no longer carry the tag of 'D' or doubtful voters, he said.
''There are 28,000 cases pending in different Foreigners' Tribunals in the state against people of the community. The cabinet has taken a historic decision of lifting the cases with immediate effect,'' Sarma said at a press conference here after the cabinet meeting.
The government believes that the Koch Rajbongshis are an indigenous community of the state and they are an inextricable part of ''our social and cultural fabric'', he asserted.
The people of this community are poor and have suffered a lot over the years, he said.
''They will no longer carry the tag of foreigners or ‘D’ voters,'' the CM said.
Foreigners Tribunals are quasi-judicial bodies, particularly in Assam, established to determine if a person residing in India is a "foreigner" as defined by the Foreigners Act of 1946, based on the Foreigners (Tribunals) Order of 1964.
These tribunals are designed to address matters related to citizenship and the presence of “foreigners” in India, specifically focusing on cases where someone is suspected of being an illegal immigrant.
There are 100 Foreigners’ Tribunals across Assam.
The Koch Rajbongshis have a sizeable presence in Assam, West Bengal, Meghalaya, and parts of Bangladesh, Nepal, and Bhutan, and they demand Scheduled Tribe status.
