'Extreme low temperature required to store Pfizer's COVID vaccine big challenge for India'
New Delhi: The extremely low temperature of minus 70 degrees Celsius required for storing a potential COVID-19 vaccine developed by Pfizer poses a big challenge for its delivery in a developing nation like India, especially in its smaller towns and rural areas where maintaining such cold chain facilities would be very difficult, AIIMS Director Dr. Randeep Guleria said on Wednesday.
Most vaccines in India need to be stored at a temperature of two to eight degrees Celsius. The lowest minimum temperature at which vaccines can be kept to maintain the cold chain in most areas in the country is minus 25 degrees Celsius, Guleria said.
He, however, said the first set of results announced by Pfizer Inc. and BioNTech SE from the Phase 3 vaccine trial, showing a 90-per cent efficacy in preventing the coronavirus infection, is quite encouraging.
"The extremely low temperature of minus 70 degrees Celsius required for the potential anti-coronavirus vaccine developed by Pfizer poses a big challenge for its delivery in a developing nation like India.
"Storing vaccines at such a low temperature and maintaining such cold chains in smaller towns and cities is going to be very difficult," Guleria said.
He stressed that the data released by the firms developing vaccines have to be studied and it has to be seen how long the immunity would last.
About the recent surge in COVID-19 cases in Delhi, Guleria said festivities or heavily crowded marketplaces may have acted as "superspreader spots" and stressed the need to remain vigilant and follow COVID-appropriate behavior such as wearing masks, maintaining physical distancing, respiratory etiquette, and hang hygiene diligently.
Delhi recorded its sharpest single-day spike of 7,830 fresh COVID-19 cases on Tuesday, which took the national capital's infection tally to over 4.5 lakh.
Pfizer Inc. and BioNTech SE on Monday said their vaccine candidate was found to be more than 90 percent effective in preventing COVID-19.
"Today is a great day for science and humanity. The first set of results from our Phase 3 COVID-19 vaccine trial provides the initial evidence of our vaccine's ability to prevent COVID-19," Pfizer Chairman and CEO Albert Bourla said.
Asked if India was considering a tie-up with Pfizer for its COVID-19 vaccine and whether the country has the infrastructure for the specialized cold chain requirement for this vaccine, the health ministry on Tuesday said the National Expert Group on Vaccine Administration for COVID-19 is in talks with all the vaccine manufacturers, including domestic and foreign ones.
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England sticking with Key, McCullum and Stokes despite Ashes humbling
London (AP): England is not sacking anybody following the 4-1 Ashes loss in Australia.
A review of the tour by the England and Wales Cricket Board, announced within hours of the final match in January, was concluded on Monday. Firing people would “be the easy thing to do,” ECB chief executive Richard Gould said but he insisted, "This is not the time to throw everything out."
Managing director Rob Key, coach Brendon McCullum and captain Ben Stokes kept their jobs after the best England side to go to Australia in 14 years lost the Ashes in 11 days with two games to spare.
“Moving people on can sometimes be the easy thing to do. That's not the route that we're going to take,” Gould said. “I've seen the driving ambition and determination that we're lucky enough to have within our leadership group to take the lessons from the Ashes and move forward.”
Gould previously was the chief executive of Bristol City soccer club and said the ECB would not follow the same route as soccer's hire-and-fire culture.
“Cricket is a very unique sport in that it takes a team of leadership ... it's not like football where there's a single point of failure or success with a manager," he said. He added the ECB would not “select or deselect management based on a popularity campaign.”
The main criticisms of England's tour were poor preparation, player misbehavior, and selection mistakes.
At a press conference at Lord's, Gould and Key said McCullum and Stokes have not had a “bust up,” they did not want McCullum to “completely change” but “to evolve,” the behavior of some players was “unprofessional,” there will be more consequences for underperforming, and a commitment to “better long-term planning” ahead of major test series.
Some changes were already implemented for the Twenty20 World Cup, where England reached the semifinals. Gould implied that performance saved McCullum.
Key acknowledged that England supporters would be disappointed to see the management team go unpunished.
“I know people want punishment and that people then should be sacked for that,” Key said. “That doesn't mean we don't feel like we've gone through some serious pain: Brendon, myself, Ben. It's been as tough a time as I think I've had.”
