First 3D-printed human corneas can aid transplants
London, May 30: In a first, British scientists have 3D printed human corneas that could cut down shortage of eye donors available for transplant.
In the research, researchers from Britain's Newcastle University, mixed stem cells (human corneal stromal cells) from a healthy donor cornea with alginate and collagen to create a solution that could be printed or a "bio-ink".
Using a simple low-cost 3D bio-printer, the bio-ink was successfully extruded in concentric circles to form the shape of a human cornea. It took less than 10 minutes to print.
"Our unique gel -- a combination of alginate and collagen -- keeps the stem cells alive whilst producing a material which is stiff enough to hold its shape but soft enough to be squeezed out the nozzle of a 3D printer," said lead author Che Connon, a professor at the varisty.
The results published in the journal, Experimental Eye Research, also stated that the stem cells could culture -- or grow.
"...we have a ready to use bio-ink containing stem cells allowing users to start printing tissues without having to worry about growing the cells separately," Connon added.
According to the researchers, there is a significant shortage of corneas available to transplant, with 10 million people worldwide requiring surgery to prevent corneal blindness as a result of diseases such as trachoma, an infectious eye disorder.
Further, the study also demonstrated that the cornea could also be built to match a patient's unique specifications.
The dimensions of the printed tissue were originally taken from an actual cornea. By scanning a patient's eye, they could use the data to rapidly print a cornea which matched the size and shape, the team explained.
"...what we have shown is that it is feasible to print corneas using coordinates taken from a patient eye and that this approach has potential to combat the world-wide shortage," Connon said.
However, the researchers admitted that further investigations on 3D printed corneas are needed before they could be used in transplants.
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Myanmar quake: India sends more humanitarian aid in C-17 aircraft
New Delhi (PTI): India on Sunday sent 31 tonnes of humanitarian aid, including replenishment stores for an Indian army field hospital unit deployed in Myanmar, to augment New Delhi's efforts to provide succour to the quake-hit neighbouring country.
The aid was sent in a C-17 Globemaster heavy-lift aircraft.
It took off from the Hindon air force station in Ghaziabad early Sunday, a senior official said.
"#OperationBrahma@IAF_MCC C> C-17 plane departs for Mandalay with 31 tons of humanitarian aid, including replenishment stores for the Indian army field hospital unit," External Affairs Minister S Jaishankar posted on X and also shared a few photos.
A 7.7-magnitude earthquake jolted Myanmar last week, with the toll rising to over 3,000 even as rescuers continue to search through the rubble for signs of life.
India mounted its relief mission named 'Operation Brahma' as a swift response to the devastation caused by the earthquake that hit Myanmar as well as Thailand on March 28.
The field hospital, under 'Operation Brahma', continues its humanitarian mission in Myanmar as the local government and its agencies also soldiered on with their efforts in relief and rescue work.
The hospital unit comprising 118 personnel was deployed in Myanmar using two C-17 heavy-lift aircraft of the IAF which had taken off from Agra on March 29.
The field hospital has been set up by the Indian Army in Mandalay.
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