New protein linked to spread of breast cancer identified
Toronto, May 7: Researchers have found that a protein that, once deactivated, could prevent the spread of an aggressive type of breast cancer to other sites in the body, a process known as metastasis.
In their study, published in the journal Cell Reports, the researchers demonstrated that a protein, AXL, influences the occurrence of metastasis in HER2-positive cancer, an aggressive type that accounts for 20 per cent of breast cancers.
In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.
The research was done on mice and with samples of tumour cells taken from cancer patients in Montreal, Canada.
In women with HER2-positive cancer, it was found that the less AXL is present, the better the survival rate.
Previously, researchers had linked the AXL protein to another type of cancer, triple negative breast cancer, but its role in in HER2-positive cancer was not known.
"Based on this discovery, a treatment targeting AXL could reduce the risk of metastasis," said one of the researchers Jean-Francois Cote, Professor at Universite de Montreal in Canada.
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“Mistake owing to communication gap,” MLA Yatnal clarifies over alleged derogatory speech on Prophet
Vijayapura: Vijayapura MLA Basanagouda Patil Yatnal has denied making any derogatory statement about Prophet Muhammad, clarifying that there was a misstatement during his speech at a Ram Navami event in Hubballi. "I did not speak about Prophet Muhammad. I meant to refer to Muhammad Ali Jinnah, but there was a mistake in the speed of speech," he said addressing reporters on Monday.
He alleged that members of the Congress, frustrated by their hooliganism and failure to collect their hafta (extortion) in Vijayapura are using the Prophet as an excuse to speak against me. “There is no culture of denigrating another religion in Hinduism. Our gurus and elders have not taught us that,” he said.
Responding to another controversy involving an audio clip in which he was allegedly threatened, Yatnal said the police are investigating the matter and that those behind it will soon be exposed. “No one can finish me. The Hindus of Karnataka are with me. If someone tries to finish me, the whole state will rise in protest,” he warned.
