It was an express trip home, lasting just 6 1/2 hours.
The astronauts, three American and one Japanese, flew back in the same capsule named Resilience in which they launched from NASA's Kennedy Space Center in November.
Their 167-day mission is the longest for astronauts launching from the US The previous record of 84 days was set by NASA's final Skylab station crew in 1974.
Saturday night's undocking left seven people at the space station, four of whom arrived a week ago via SpaceX.
Earthbound! NASA astronaut Victor Glover tweeted after departing the station.
One step closer to family and home!
Glover along with NASA's Mike Hopkins and Shannon Walker and Japan's Soichi Noguchi should have returned to Earth last Wednesday, but high offshore winds forced SpaceX to pass up a pair of daytime landing attempts.
Managers switched to a rare splashdown in darkness, to take advantage of calm weather.
SpaceX had practiced for a night time return, just in case, and even recovered its most recent station cargo capsule from the Gulf of Mexico in darkness. Infrared cameras tracked the capsule as it re-entered the atmosphere; it resembled a bright star streaking through the night sky.
All four main parachutes could be seen deploying just before splashdown, which was also visible in the infrared.
Apollo 8 NASA's first flight to the moon with astronauts ended with a predawn splashdown in the Pacific near Hawaii on Dec. 27, 1968. Eight years later, a Soviet capsule with two cosmonauts ended up in a dark, partially frozen lake in Kazakhstan, blown off course in a blizzard.
That was it for night time crew splashdowns until Sunday.
Despite the early hour, the Coast Guard was out in full force to enforce an 11-mile (18-kilometer) keep-out zone around the bobbing Dragon capsule. For SpaceX's first crew return in August, pleasure boaters swarmed the capsule, a safety risk.
Once aboard the SpaceX recovery ship, the astronauts planned to hop on a helicopter for the short flight to shore, then catch a plane straight to Houston for a reunion with their families.
Their capsule, Resilience, will head back to Cape Canaveral for refurbishment for SpaceX's first private crew mission in September. The space station docking mechanism will be removed, and a brand new domed window put in its place.
A tech billionaire has purchased the entire three-day flight, which will orbit 75 miles (120 kilometers) above the space station. He'll fly with a pair of contest winners and a physician assistant from St. Jude Children's Research Hospital, his designated charity for the mission.
SpaceX's next astronaut launch for NASA will follow in October.
NASA turned to private companies to service the space station, after the shuttle fleet retired in 2011. SpaceX began supply runs in 2012 and, last May, launched its first crew, ending NASA's reliance on Russia for astronaut transport.
Boeing isn't expected to launch astronauts until early next year.
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ISLAMABAD: At least two more cases of poliovirus were reported in Pakistan, taking the number of infections to 52 so far this year, a report said on Friday.
“The Regional Reference Laboratory for Polio Eradication at the National Institute of Health has confirmed the detection of two more wild poliovirus type 1 (WPV1) cases in Pakistan," an official statement said.
The fresh infections — a boy and a girl — were reported from the Dera Ismail Khan district of Khyber-Pakhtunkhwa province.
“Genetic sequencing of the samples collected from the children is underway," the statement read. Dera Ismail Khan, one of the seven polio-endemic districts of southern Khyber Pakhtunkhwa province, has reported five polio cases so far this year.
Of the 52 cases in the country this year, 24 are from Balochistan, 13 from Sindh, 13 from Khyber Pakhtunkhwa, and one each from Punjab and Islamabad.
There is no cure for polio. Only multiple doses of the oral polio vaccine and completion of the routine vaccination schedule for all children under the age of five can keep them protected.