Wireless device to detect heart dysfunction in cancer survivors
New York, June 23 : Scientists have designed a novel wireless device which may accurately detect heart dysfunction in children who have survived cancer.
Childhood cancer survivors are advised to undergo screening for the detection of heart dysfunction because of known anthracycline-induced cardiotoxicity.
However, screening with echocardiography -- the standard of care for monitoring heart function -- can be highly variable and limited.
Another alternative is cardiac magnetic resonance (CMR) imaging, which is expensive and is not widely accessible.
In the study, the team tested Vivio -- a prototype handheld instrument which collects pulse waves and phonocardiogram data from the carotid artery. The results showed that the device was accurate and it displayed a low false-negative rate as compared to CMR imaging.
"This study is the first step in thinking about new paradigms of long-term monitoring and care delivery for cancer survivors who are at risk for severe and life-threatening health conditions," said Saro Armenian, Director at City of Hope National Medical Centre in California.
The study, published in the journal Clinical Cancer Research, involved data from 191 patients exposed to anthracycline chemotherapy.
The data of the participants was collected using Vivio which then streamed wirelessly to a compatible device such as a smart phone or e-tablet.
This mobile health platform negates the need for result interpretation and allows for real-time monitoring of heart health, explained Armenian.
Using a specialised algorithm, Vivio measures the left ventricular ejection fraction (LVEF), which is commonly used to assess heart function and measures the percentage of blood ejected from the left ventricle of the heart, Armenian added.
However, the author said that Vivio is not currently intended to replace echocardiography or CMR imaging.
"One possible implementation of Vivio could be for preliminary screening," Armenian explained.
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Axar shifts focus to next IPL after KKR all but end DC's campaign
New Delhi (PTI): A beleaguered Axar Patel admitted that both his team's batters and bowlers let the side down after Delhi Capitals suffered a humiliating eight-wicket defeat to Kolkata Knight Riders, virtually ending their IPL 2026 playoff hopes, while indicating the team had already begun looking ahead to the next season.
DC endured a miserable outing at home, managing only 142/8, which Kolkata Knight Riders chased down in just 14.2 overs, powered by a blistering unbeaten 100 from Finn Allen and his destructive stand with Cameron Green (33 not out) as the visitors tore apart the bowling attack.
With just eight points from 11 matches, DC are eighth on the table, while KKR revived their playoff hopes with a resurgent run, moving to seventh with nine points from 10 outings, though their road to the knockouts still remains difficult.
"For now, we'll go back and think about the mistakes we made. After that, obviously there's still a long journey ahead and next year will come too. So we'll think about what plans we can make for next year and what approach we should take," said Axar after the match.
"Based on that, we can also look at the players sitting on the bench and decide who can be given opportunities and what changes we can make," he added, hinting at a possible major overhaul next season.
With 200-plus totals becoming the norm this season, 142 was always going to be inadequate, and Axar admitted the score was well below par while also pointing out at poor judgement shown by the spinners while defending the modest total.
"I think the runs were definitely below par and at the same time the spinners made quite a few mistakes. Looking at the way the pitch behaved, I feel the spinners did make errors.
"At the same time, we lost five wickets in two-three overs, and I think that's where the momentum slipped away from us. That's probably something we need to think about because the same thing happened against CSK...we started well, and then suddenly wickets kept falling," he added.
He admitted the solutions to the issues could be found but players need to show the right mindset and character.
"See, you can't solve it in a complicated way. So, I think it's more about applying the right mindset. Even if you lose one or two wickets, you can still spend time at the crease and play through it. I think that's what needs to be applied, when wickets are falling in clusters, you need to absorb the pressure for an over or two," opined Axar.
KKR skipper Ajinkya Rahane was pleased to see a struggling Finn Allen finally rediscover his touch with the bat.
"I'm really happy for Finn Allen. He was struggling first four or five games, working really hard, but the way he batted tonight was fantastic. But I want to praise our bowlers again.
"We did well because of them. And they've been doing it so well consistently, especially those middle overs and the death overs. Our spinners, Sunil Narine, Varun (Chakravarthy) and Anukul Roy, have been fantastic," he said.
"Fielding-wise, yes, we are working really hard. Our fielding coach has been really strict with us. And that's what has been helping us. The result which you've been seeing about the catches and the ground fielding, credit goes to our fielding coach as well," he added.
