In an unconventional approach to treating cancer, Croatian virologist Beata Halassy, 49, recently treated her recurrent breast cancer using lab-grown viruses in a procedure known as oncolytic virotherapy (OVT). With the tumour shrinking significantly, Halassy was able to undergo successful surgical removal and has remained cancer-free for four years. This unusual self-treatment has sparked discussions around the ethics of self-experimentation in medicine.
The treatment, detailed in the journal ‘Vaccines’, involved injecting the tumour with viruses she cultivated herself. Halassy used two viruses consecutively – a measles virus and vesicular stomatitis virus (VSV), both known to target her tumour type and previously trialled in other forms of cancer. Over two months, she administered the injections with research-grade material prepared in her lab. Monitoring by her oncologists allowed her to shift to conventional chemotherapy if necessary, though the treatment proceeded without significant side effects. Ultimately, the tumour detached from surrounding tissue, facilitating its surgical removal. Post-surgery analysis confirmed an immune response, with lymphocytes actively infiltrating the tumour.
Although the approach proved effective, Halassy faced challenges in publishing her findings, with journals hesitant over ethical concerns. Jacob Sherkow, a law and medicine researcher, pointed out the ethical risks of promoting self-experimentation, as it may encourage patients to bypass standard treatments. However, Sherkow noted the value of preserving the knowledge gained from such cases.
OVT remains experimental, with some forms approved for metastatic melanoma in the U.S., but no official treatment for breast cancer. Halassy, who is not an oncologist, emphasised that her expertise in virology gave her confidence in attempting the treatment, though she warns others not to view self-treatment as a first option in cancer care.
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Pilibhit (PTI): A 19-day-old elephant calf, brought from Bijnor, was placed under care at the Pilibhit Tiger Reserve (PTR) on Sunday, an official said and added that the calf got separated from its mother in the forest area of Bijnor.
The calf was born on December 2 in the Bijnor forest area and got separated from its mother shortly after birth, the official said.
The forest department made several attempts to reunite it with its mother, but without any success. To ensure the calf's safety and better care, it was decided to transfer it to the Pilibhit Tiger Reserve on the instructions of senior officials.
On Saturday, Deputy Director Manish Singh received the calf. Special arrangements have been made in the reserve for its care. It has been kept in a safe and clean environment to provide it with a natural setting and protect it from external noise and disturbances.
Singh told reporters that raising an 19-day-old calf is challenging.
It requires a special diet as a substitute for mother's milk and constant monitoring.
He said a special team has been formed to provide 24-hour care. Since the calf is very young, it is being cared for like a newborn baby.
According to Singh, the primary responsibility for monitoring the calf's health has been entrusted to PTR's veterinarian, Dr Daksh Gangwar. Under his supervision, a complete record of the calf's health checkups, diet, and body temperature is being maintained. The team is ensuring that the calf does not contract any infection.
