Houston: A 14-year-old Indian-American girl has won a USD 25,000 young scientist challenge for a discovery that could provide a potential treatment for COVID-19.
Anika Chebrolu, an eighth grader from Frisco in Texas, won the 3M Young Scientist Challenge, regarded as the US' premier middle school science competition, for her work using in-silico methodology for drug discovery to find a molecule that can selectively bind to the Spike protein of SARS-CoV-2 virus in an attempt to find a cure for the coronavirus pandemic, according to the 3M Challenge website.
3M is an American manufacturing company based in Minnesota.
Chebrolu decided to take part in the Young Scientist Challenge after she battled a severe influenza infection last year. She wanted to find a cure for influenza. However, that all changed after the COVID-19 pandemic hit, the website said.
I was drawn towards finding effective cures for influenza disease after a severe bout of the infection last year, Chebrolu said.
I would like to learn more from 3M scientists to pursue my drug development and with their help, would like to conduct in-vitro and in-vivo testing of my lead drug candidate, she said.
Chebrolu was one of the 10 finalists in this year's 3M Young Scientist Challenge. In addition to the prize money, she was also awarded an exclusive 3M Mentorship.
As a finalist, she worked with 3M Corporate Scientist Dr Mahfuza Ali, who mentored Chebrolu one-on-one throughout the summer. Together, they transformed her idea from concept to reality.
Dr Ali helped Chebrolu perfect her innovation through the scientific method, and she presented her project to a judging panel of scientists and leaders. Each finalist was evaluated on a series of challenges and the presentation of their completed innovation.
"I am extremely humbled at being selected America's Top Young Scientist as all of the finalists had amazing projects and were extremely well-rounded individuals," Chebrolu said.
"Science is the basis of life and the entire universe and we have a long way to go understand it fully," said Chebrolu, who wants to become a medical researcher and professor.
Talking to CNN, Chebrolu said, "The last two days, I saw that there is a lot of media hype about my project since it involves the SARS-CoV-2 virus and it reflects our collective hopes to end this pandemic as I, like everyone else, wish that we go back to our normal lives soon."
Chebrolu said she was inspired to find potential cures to viruses after learning about the 1918 flu pandemic and finding out how many people die every year in the US despite annual vaccinations and anti-influenza drugs on the market.
"Chebrolu has an inquisitive mind and used her curiosity to ask questions about a vaccine for COVID-19," Dr Cindy Moss, a judge for the competition, told CNN.
"Her work was comprehensive and examined numerous databases. She also developed an understanding of the innovation process and is a masterful communicator. Her willingness to use her time and talent to help make the world a better place gives us all hope," Moss said.
Chebrolu said that winning the prize and title of top young scientist is an honour, but her work isn't done.
Her next goal, she says, is to work alongside scientists and researchers who are fighting to "control the morbidity and mortality" of the pandemic by developing her findings into an actual cure for the virus.
"My effort to find a lead compound to bind to the spike protein of the SARS-CoV-2 virus this summer may appear to be a drop in the ocean, but still adds to all these efforts," she told CNN.
"How I develop this molecule further with the help of virologists and drug development specialists will determine the success of these efforts," she said.
Denise Rutherford, senior vice president of Corporate Affairs at 3M in his congratulatory message said that amidst the challenges of a global pandemic, quality STEM education for all has become an even more urgent need.
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Thiruvananthapuram (PTI): Buoyed by the strong performance of the Congress-led UDF in the local body polls, KPCC president Sunny Joseph said on Saturday that the front's results indicated the people had rejected the LDF government.
According to early trends, the UDF was leading in more grama panchayats, block panchayats, municipalities and corporations than the LDF.
The local body polls were held in two phases in the state earlier this week.
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Speaking to reporters here, Joseph said the people of Kerala had extended their support to the UDF.
"We could expose the LDF government’s anti-people stance and the people understood it. The LDF’s fake propaganda was rejected by the people. The UDF is moving towards a historic victory," he said.
He said a united effort, proper preparations, good candidate selection and hard work had resulted in the Congress and the UDF’s victory in the elections.
Asked about the prospects in the Thiruvananthapuram Corporation, Joseph said the party was studying the matter and would comment later.
LDF convenor T P Ramakrishnan said the results would be closely examined.
According to him, the government had done everything possible for the people.
"Why such a verdict happened will be examined at the micro level. People’s opinion will be considered and further steps will be taken," he said.
He added that decisions would be taken after analysing the results. "If any corrective measures are required, we will initiate them and move forward," he said.
AICC leader K C Venugopal said the results showed that people had begun ousting those who, he alleged, were responsible for the loss of gold at Lord Ayyappa’s temple.
"This trend will continue in the Assembly elections as well. It is an indication that the people are ready to bring down the LDF government," he said.
Venugopal said the UDF had registered victories even in CPI(M) and LDF strongholds.
"I congratulate all UDF workers for their hard work. Congress workers and leaders worked unitedly," he said.
Referring to remarks made by Chief Minister Pinarayi Vijayan against the Congress on polling day, Venugopal said the voters had responded through the verdict.
"I do not know whether the chief minister understands that the people are against him. Otherwise, he does not know the sentiment of the people. The state government cannot move an inch further," he said.
He said the results indicated a strong comeback for the UDF in Kerala.
Asked whether the Sabarimala gold loss issue had affected the LDF in the local polls, Venugopal said the CM and the CPI(M) state secretary did not take the issue seriously.
"We took a strong stand on the matter. The BJP played a foul game in it," he alleged.
On the BJP's role in the local body elections, Venugopal alleged that the party operated with the CPI(M) 's tacit support.
"The CPI(M) supported the central government on issues such as PM-SHRI, labour codes and corruption in national highway construction. The CPI(M) is facing ideological decline, and the state government’s policies are against the party’s own decisions," he said.
Meanwhile, LDF ally Kerala Congress (M) leader Jose K Mani said the party could not win all the wards it had expected in the elections.
He congratulated winners from all parties and said the party would closely examine the losses and identify shortcomings. "Later, we will take corrective measures," he added.
Senior Congress leader and MP Rajmohan Unnithan said the trends in the local body elections indicated that the UDF would return to power in the 2026 Assembly elections.
"We will win 111 seats as in 1977 and return to power in 2026. The anti-government sentiment of the people is reflected in the elections," he said.
Unnithan said the people were disturbed and unhappy with the present government.
"The trend indicates the end of the LDF government," he added.
CPI(M) MLA M M Mani said the people had shown ingratitude towards the LDF despite benefiting from welfare schemes.
"After receiving all welfare schemes and living comfortably, people voted against us due to some temporary sentiments. Is that not ingratitude," he asked.
Mani said no such welfare initiatives had taken place in Kerala earlier.
"People are receiving pensions and have enough to eat. Even after getting all this, they voted against us. This is what can be called ingratitude," he said.
Muslim League state president Panakkad Sayyid Sadiq Ali Shihab Thangal said the results were beyond expectations.
"The outcome points towards the Secretariat in Thiruvananthapuram, indicating that a change of government is imminent. We are going to win the Assembly election," he said.
