Trio win Nobel Medicine Prize for work on cells, oxygen
Stockholm: US researchers William Kaelin and Gregg Semenza and Britain's Peter Ratcliffe on Monday shared the Nobel Medicine Prize for discoveries on how cells sense and adapt to oxygen availability, the Nobel Assembly said.
"They established the basis for our understanding of how oxygen levels affect cellular metabolism and physiological function," the jury said.
Their research has "paved the way for promising new strategies to fight anemia, cancer and many other diseases."
The jury said the trio had identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen, which is central to a large number of diseases.
"Intense ongoing efforts in academic laboratories and pharmaceutical companies are now focused on developing drugs that can interfere with different disease states by either activating, or blocking, the oxygen-sensing machinery," the jury said.
Kaelin works at the Howard Hughes Medical Institute in the US, while Semenza is director of the Vascular Research Program at the John Hopkins Institute for Cell Engineering.
Ratcliffe is director of clinical research at the Francis Crick Institute in London, and director of the Target Discovery Institute in Oxford.
The three will share the Nobel prize sum of nine million Swedish kronor (about USD 914,000).
They will receive their prize from King Carl XVI Gustaf at a formal ceremony in Stockholm on December 10, the anniversary of the 1896 death of scientist Alfred Nobel who created the prizes in his last will and testament.
Last year, the honour went to immunologists James Allison of the US and Tasuku Honjo of Japan, for figuring out how to release the immune system's brakes to allow it to attack cancer cells more efficiently.
The winners of this year's Physics Prize will be revealed on Tuesday, followed by the Chemistry Prize on Wednesday.
The Literature Prize will be announced on Thursday, with two laureates to be crowned after a sexual harassment scandal forced the Swedish Academy to postpone the 2018 award, for the first time in 70 years.
The Peace Prize will follow on Friday, with bookies predicting a win for Swedish teen climate activist Greta Thunberg on betting sites such as Ladbrokes.
The Economics Prize will wrap up the Nobel prize season on Monday, October 14.
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Two Delhi men held for BMTC bus phone thefts in Bengaluru
Bengaluru: Whitefield police have arrested two men from Delhi for allegedly stealing mobile phones from passengers travelling in Bengaluru Metropolitan Transport Corporation (BMTC) buses and solved 14 theft cases, officials said on Tuesday.
The arrested accused have been identified as Jai Chand (25), who worked at a hotel in Delhi, and Tarun (34), an autorickshaw driver in Delhi.
Officials said on January 24, a Mahadevapura resident lodged a complaint that his iPhone 15 Plus was stolen while he was travelling on a BMTC bus towards Whitefield.
Based on the complaint, police registered a case and arrested two suspects within an hour near a lodge on Hosa Road. During the arrest, the police found a bag containing several stolen mobile phones.
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“During interrogation, the suspects confessed that they were stealing mobile phones from passengers travelling in BMTC buses. They had also committed thefts during a concert held under the Channarayapatna police station limits on January 23,” the police said.
Investigations revealed that the accused had travelled from Delhi for the concert and stolen mobile phones from the audience. A third suspect is at large and is likely hiding in the Shahdara area of Delhi.
One of the victims, a YouTuber, raised the theft issue in February in a post on X.
“Here is my (FIR No 0013/2026 is registered in Channarayapatana PS. Your GSC No. is PO1814260100013) request @DelhiPolice @BlrCityPolice to plz look into this & get my device back since it's my work phone & I am a youtuber, all my data is there! someone plz help. @dcpwhitefield,” Anirban Sarkar posted on X on February 6.
Police have recovered 14 mobile phones of various brands, collectively valued at about Rs 9 lakh, from the accused. The two were produced before the court and remanded in judicial custody.
In total, one case from Whitefield and 13 from Channarayapatna police stations were detected. Further investigation is underway.
