Kyiv (AP): Ukraine says Russia launched an intercontinental ballistic missile overnight targeting Dnipro city in the central-east of the country, which, if confirmed, would be the first time Moscow has used such a missile in the war.

In a statement Thursday on the Telegram messaging app, Ukraine's air force did not specify the exact type of missile, but said it was launched from Russia's Astrakhan region, which borders the Caspian Sea.

It said an intercontinental ballistic missile was fired at Dnipro city along with eight other missiles, and that the Ukrainian military shot down six of them.

Two people were wounded as a result of the attack, and an industrial facility and a rehabilitation centre for people with disabilities were damaged, according to local officials.

While the range of an ICBM would seem excessive for use against Ukraine, such missiles are designed to carry nuclear warheads, and the use of one would serve as a chilling reminder of Russia's nuclear capability and a powerful message of potential escalation.

The attack comes two days after Russian President Vladimir Putin signed a revised nuclear doctrine that formally lowers the threshold for the country's use of nuclear weapons. Ukraine on Tuesday fired several American-supplied longer-range missiles and reportedly fired UK-made Storm Shadows on Wednesday into Russia.

The Russian Defence Ministry said in a statement Thursday that its air defence systems shot down two British-made Storm Shadow missiles, six HIMARS rockets, and 67 drones. The announcement came in the ministry's daily roundup regarding the military actions in Ukraine.

The statement didn't say when or where exactly it happened or what the missiles were targeting. This is not Moscow's first public announcement of the shooting down of Storm Shadow missiles, as Russia earlier reported downing some over the annexed Crimean Peninsula.

The developments come as the war has taken on a growing international dimension with the arrival of North Korean troops to help Russia on the battlefield — a development that US officials said prompted U.S. President Joe Biden's policy shift on allowing Ukraine to fire longer-range US missiles into Russia. The Kremlin responded with threats to escalate further.

Putin has previously warned the US and other NATO allies that allowing Ukraine to use Western-supplied longer-range weapons to hit Russian territory would mean that Russia and NATO are at war.

And the new doctrine allows for a potential nuclear response by Moscow even to a conventional attack on Russia by any nation that is supported by a nuclear power.

While the doctrine envisions a possible nuclear response by Russia to a conventional strike, it is formulated broadly to avoid a firm commitment to use nuclear weapons and keep Putin's options open.

 

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ISLAMABAD: At least two more cases of poliovirus were reported in Pakistan, taking the number of infections to 52 so far this year, a report said on Friday.

“The Regional Reference Laboratory for Polio Eradication at the National Institute of Health has confirmed the detection of two more wild poliovirus type 1 (WPV1) cases in Pakistan," an official statement said.

The fresh infections — a boy and a girl — were reported from the Dera Ismail Khan district of Khyber-Pakhtunkhwa province.

“Genetic sequencing of the samples collected from the children is underway," the statement read. Dera Ismail Khan, one of the seven polio-endemic districts of southern Khyber Pakhtunkhwa province, has reported five polio cases so far this year.

Of the 52 cases in the country this year, 24 are from Balochistan, 13 from Sindh, 13 from Khyber Pakhtunkhwa, and one each from Punjab and Islamabad.

There is no cure for polio. Only multiple doses of the oral polio vaccine and completion of the routine vaccination schedule for all children under the age of five can keep them protected.