Berlin: The World Health Organization says it is ending a trial into whether anti-malaria drug hydroxychloroquine helps patients hospitalised with COVID-19.

WHO said Saturday it has accepted the recommendation from the committee overseeing the trial to discontinue testing of hydroxychloroquine and lopinavir/ritonavir, a drug combination used to treat HIV/AIDS. The drugs were being compared with standard care for hospitalized patients.

WHO says a review of the interim results showed hydroxychloroquine and lopinavir/ritonavir produce little or no reduction in the mortality of hospitalized COVID-19 patients when compared to standard of care.

The agency adds that while there was no solid evidence of increased mortality for hospitalized patients given the drugs, there were some associated safety signals in the clinical laboratory findings of an associated trial.

WHO says the decision won't affect possible trials on patients who aren't hospitalized, or on those receiving the drugs before potential exposure to the coronavirus or shortly afterward.

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Budapest/Washington: US Vice President J D Vance has said that Lebanon was never included in the ceasefire understanding with Iran, describing the confusion as a “legitimate misunderstanding”.

Speaking to reporters before departing from Hungary, Vance said, “I think the Iranians thought that the ceasefire included Lebanon and it just didn’t. We never made that promise.”

He stressed that the United States had not included Lebanon in the scope of the ceasefire at any stage.

His remarks come amid continued Israeli strikes in Lebanon, where more than 200 people were reported killed, even as ceasefire talks between Iran and the US move forward.

Vance said Israel had “offered … to check themselves a little bit in Lebanon because they want to make sure that our negotiation is successful”.

He warned that if Iran allows the situation in Lebanon to affect the negotiations, it could derail the talks.

“If Iran wants to let this negotiation fall apart in a conflict where they were getting hammered over Lebanon, which has nothing to do with them and which the United States never once said was part of the ceasefire, that’s ultimately their choice,” he said.