'Magical' royal bee jelly offers promise to combat cancer: Study
New York, July 23 : Royal jelly -- a natural bee product -- long known for its mysterious growth effects on future queen honey bees, while hailed by some as an anti-ageing, cholesterol-lowering super supplement, might also help fight cancer, finds new research.
Royal jelly also called "bee milk", looks like white snot. Besides water, it also contains a combination of proteins and sugars.
The findings showed this "queen magic" affects cell signalling and growth in cancer cells.
However, how this actually happens and its potential benefit to humans, has remained a mystery to scientists.
"The exact structure of the key protein in royal jelly remains unknown. But it is expected to act through the epidermal growth factor (or EGF) receptor -- the main pathway targeted by cancer therapeutics today," Daryl Klein, Assistant Professor at Yale University in Connecticut, US, said in a statement.
Klein's lab studies cell signalling, and how these signals can be "tuned" in different ways.
Using commercial jelly shipped from China, initial studies from Klein's lab have started to resolve the oligomer structure of MRJP-1 (major royal jelly protein).
However, the scientists found that resolution stalled around 11 Angstroms -- not enough to reveal the potential secrets hidden in the jelly.
They fear that the commercially available product may have been the limiting factor.
"We've bought commercial royal jelly, but it goes through a lot of handling -- freezing, thawing and re-freezing -- before it gets to us, which could affect the ultimate resolution we can see in this protein and how we can do functional tests on it," added Tongqing Li, post-doctoral associate at the varsity.
Researchers are now hoping to extract royal jelly from the university's campus to find out "how it modifies cell growth across different species, and how it might modify cancer cell signalling," Klein said.
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Donald Trump sends Diwali greetings, condemns attacks on Hindus in Bangladesh
Washington, Oct 31: Sending Diwali greetings, former president Donald Trump, who is the Republican presidential candidate, on Thursday condemned the attack on Hindus in Bangladesh, vowed to strengthen ties with India and described Prime Minister Narendra Modi as his good friend.
Bangladesh, he said, remains in a total state of chaos and alleged that his Democratic rival Vice President Kamala Harris and her boss President Joe Biden have ignored Hindus across the world and in America.
“I strongly condemn the barbaric violence against Hindus, Christians, and other minorities who are getting attacked and looted by mobs in Bangladesh, which remains in a total state of chaos,” Trump said in a post on Truth Social.
This is for the first time that Trump has spoken on the issue of Bangladesh. Hundreds of Hindus were killed in July-August in Bangladesh when a students’ agitation turned into massive protests leading to then prime minister Sheikh Hasina to flee the country on August 5.
“It would have never happened on my watch. Kamala and Joe have ignored Hindus across the world and in America. They have been a disaster from Israel to Ukraine to our own Southern Border, but we will Make America Strong Again and bring back Peace through Strength,” he said.
“We will also protect Hindu Americans against the anti-religion agenda of the radical left. We will fight for your freedom. Under my administration, we will also strengthen our great partnership with India and my good friend, Prime Minister Modi,” Trump said.
“Kamala Harris will destroy your small businesses with more regulations and higher taxes. By contrast, I cut taxes, cut regulations, unleashed American energy, and built the greatest economy in history. We will do it again, bigger and better than ever before and we will Make America Great Again,” he said.
“Also, Happy Diwali to All. I hope the Festival of Lights leads to the Victory of Good over Evil,” said the former president, who is in a close fight with Harris for the November 5 presidential elections.
