New York, June 22: Scientists, including one of Indian-origin, have found that a brain region -- associated with cognitive behaviours, decision making, and moderating social behaviour -- determines our overall level of consciousness.
The study, conducted on rats, provided evidence that the prefrontal cortex has a switchboard-like relationship with other areas of the brain, helping to ignite awareness of visual information.
"The study suggests that the prefrontal cortex has the potential to play a role in coordinating the level of consciousness," said George Mashour from the University of Michigan.
The results could also be explored for applications in people with disorders of consciousness, such as coma or vegetative states.
"It's very difficult and dangerous to directly intervene at the level of arousal centres in the brainstem because of its location, small size, and nearby vital functions.
"Maybe the prefrontal cortex is an accessible gateway to some of those other arousal systems that could be leveraged in a clinical setting outside of anesthesia," he said.
In the study, published in the journal Current Biology, the team gave anesthetised rats with a common anesthetic used in humans and exposed their prefrontal and parietal lobe -- a brain region associated with processing sensory information and interpreting visual information -- to drugs that ramped up the effect of neurotransmitters and measured their brain activity and behaviour.
To see what had the causal power to take an unconscious brain receiving ongoing anesthesia and wake it up, the team targeted two neurotransmitters that are associated with wakefulness: acetylcholine and norepinephrine, said Dinesh Pal, from the varsity.
The findings showed that when exposed to an acetylcholine-receptor activator, the rats' brain waves -- normally slow during sleep and anesthesia -- sped up.
But rats were able to start behaving as though they were awake only with prefrontal cortex stimulation, all while continuing to receive the same level of anesthesia that is used clinically for surgery in humans.
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Guwahati, Apr 4 (PTI): The Assam cabinet has decided to lift all cases pending against people from the Koch Rajbongshi community in the Foreigners' Tribunals, Chief Minister Himanta Biswa Sarma said on Friday.
They will also no longer carry the tag of 'D' or doubtful voters, he said.
''There are 28,000 cases pending in different Foreigners' Tribunals in the state against people of the community. The cabinet has taken a historic decision of lifting the cases with immediate effect,'' Sarma said at a press conference here after the cabinet meeting.
The government believes that the Koch Rajbongshis are an indigenous community of the state and they are an inextricable part of ''our social and cultural fabric'', he asserted.
The people of this community are poor and have suffered a lot over the years, he said.
''They will no longer carry the tag of foreigners or ‘D’ voters,'' the CM said.
Foreigners Tribunals are quasi-judicial bodies, particularly in Assam, established to determine if a person residing in India is a "foreigner" as defined by the Foreigners Act of 1946, based on the Foreigners (Tribunals) Order of 1964.
These tribunals are designed to address matters related to citizenship and the presence of “foreigners” in India, specifically focusing on cases where someone is suspected of being an illegal immigrant.
There are 100 Foreigners’ Tribunals across Assam.
The Koch Rajbongshis have a sizeable presence in Assam, West Bengal, Meghalaya, and parts of Bangladesh, Nepal, and Bhutan, and they demand Scheduled Tribe status.