Nobel Prize in medicine goes to 3 scientists for work on peripheral immune tolerance
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Stockholm (AP): Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance.
Peripheral immune tolerance is one way the body helps keep the immune system from getting out of whack and attacking your own tissues instead of foreign invaders.
The award is the first of the 2025 Nobel Prize announcements and was announced by a panel at the Karolinska Institute in Stockholm.
Last year's prize was shared by Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that help control what the cells do and when they do it.
Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in economics October 13.
The award ceremony will be held December 10, the anniversary of the death of Alfred Nobel, who founded the prizes. Nobel was a wealthy Swedish industrialist and the inventor of dynamite. He died in 1896.
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Parents fear uncertainty after Karnataka govt rules out age limit relaxation for Class 1 admission
Bengaluru: The Karnataka government has ruled out any relaxation of the minimum age limit for admission to Class 1 beginning with the academic year 2026-27. Following the refusal, a group of parents continues to press for leniency.
Parents of children who fall under the age of six by a small margin on the cut-off date have met Deputy Chief Minister D K Shivakumar and senior officials from the Department of School Education and Literacy to request an exemption. School Education and Literacy Minister Madhu Bangarappa said that the government will not change its decision, as reported by Deccan Herald.
According to the minister, children must be six years old by June 1 to be eligible for admission to Class 1. beginning with the 2026-27 academic year. He noted that the previous relaxation was a one-time measure that was clearly confined to the 2025-26 academic year.
“If such requests are entertained every year, it will never end. While granting relaxation last year, it was explicitly stated that it applied only to one academic year. From 2026-27 onwards, the rule will be strictly implemented,” Bangarappa was quoted by DH.
Parents argue that the rigid cut-off is affecting children who are short by a few days. One parent was quoted by DH as saying that his daughter would be 12 days short of completing six years on June 1. Such parents would be forced to repeat a year despite being academically ready. Others pointed out that children promoted from LKG to UKG during the 2025-26 academic year are now facing uncertainty over their transition to Class 1.
Few parents also recalled that earlier, admissions were allowed for children aged between five years and 10 months and six years. Parents saw it as a more practical approach, with children born in November and December being disproportionately affected.
The issue of age criterion goes back to a government order issued in July 2022. The order mandated six years as the minimum age for Class 1 admission. Parents of children already enrolled in pre-primary classes, protested against the order and the state deferred implementation, announcing that the rule would come into force from the 2025-26 academic year.
After renewed pressure, the government granted a one-year relaxation for 2025-26, citing the large number of students affected and in consultation with the State Education Policy Commission. While announcing the exemption, the minister had stated that no further concessions would be allowed.
