WHO issues global alert on rare vision loss linked to popular diabetes, weight loss drugs
Geneva: The World Health Organization (WHO) has issued a global safety alert warning of a rare but potentially irreversible vision condition associated with popular diabetes and weight-loss drugs containing semaglutide, including Ozempic, Rybelsus, and Wegovy.
The alert, released on 27 June, highlights the risk of non-arteritic anterior ischaemic optic neuropathy (NAION), a condition that can lead to sudden, painless, and irreversible loss of vision, typically in one eye.
“There is currently no effective treatment available for NAION, and the vision loss is generally irreversible,” the WHO stated in its warning.
The European Medicines Agency (EMA) has already acted on this risk by updating the safety profiles of these drugs. Following a comprehensive safety review, the agency’s Pharmacovigilance Risk Assessment Committee (PRAC) recommended that NAION be listed as a “very rare” side effect, potentially affecting up to 1 in 10,000 users.
Semaglutide, a GLP-1 receptor agonist, has seen widespread use globally for treating type 2 diabetes and obesity. However, the growing popularity of these drugs has also brought new safety concerns to light.
NAION is considered the second most common optic neuropathy after glaucoma and can present without pain, making early detection more challenging. Common symptoms include sudden vision loss and optic disc swelling.
The WHO noted that its global adverse event database, VigiBase, had received several individual case safety reports of NAION linked to semaglutide use from multiple countries. After assessing these reports during its May 2025 meeting, the WHO Advisory Committee on Safety of Medicinal Products (ACSoMP) recommended revising semaglutide’s risk management plans.
Healthcare professionals worldwide are now being urged to inform patients about this potential risk and to remain vigilant. Patients currently using semaglutide or considering it are advised to seek immediate medical help if they experience any sudden changes in vision.
The alert is part of continued pharmacovigilance efforts around GLP-1-based medications, which have transformed diabetes and obesity care but continue to face evolving scrutiny as their use expands.
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Indian mobile hospital treats over 2,200 cyclone-hit people as New Delhi ramps up relief efforts in
Colombo (PTI): A mobile hospital set up by India in Sri Lanka has provided medical care to over 2,200 people affected by Cyclone Ditwah, as New Delhi ramped up its assistance to the flood-ravaged island nation with engineering support and delivery of fresh relief consignments, the Indian mission here said on Sunday.
Sri Lanka has been grappling with widespread flooding, landslides and severe infrastructure collapse triggered by the cyclone, leaving several districts isolated and severely straining the country's disaster-response capacity.
At least 627 people have been killed and 190 remain missing as of Sunday noon due to catastrophic floods and landslides caused by extreme weather conditions since November 16.
Sharing a social media post by the Ministry of External Affairs on its X handle, the Indian High Commission said a field hospital set up by India in Mahiyanganaya near Kandy has provided medical care to more than 2,200 people affected by the cyclone since December 5.
The hospital has also performed 67 minor procedures and three surgeries, it said. The field hospital was airlifted to Sri Lanka by an IAF C-17 aircraft along with a 78-member Indian medical team on Tuesday.
In another post, the mission said Indian Army engineers, working with Sri Lanka Army Engineers and the Road Development Authority, in Kilinochchi have begun removing a damaged bridge on the Paranthan–Karachchi–Mullaitivu (A35) road, a key route disrupted by the cyclone.
"This joint effort marks another step toward restoring vital connectivity for affected communities," it said.
India has additionally sent nearly 1,000 tonnes of food items and clothing contributed by the people of Tamil Nadu. Of these, about 300 tonnes reached Colombo on Sunday morning aboard three Indian Naval ships.
High Commissioner Santosh Jha handed over the supplies to Sri Lankan Minister for Trade, Commerce, Food Security and Cooperative Development Wasantha Samarasinghe.
India, on November 28, launched 'Operation Sagar Bandhu', a Humanitarian Assistance and Disaster Relief (HADR) initiative, to aid Sri Lanka in its recovery from the devastation caused by Cyclone Ditwah.
Since the launch of the operation, India has provided about 58 tonnes of relief material, including dry rations, tents, tarpaulins, hygiene kits, essential cloths, water purification kits and about 4.5 tonnes of medicines and surgical equipment, the Indian mission said in a press release on Sunday.
Another 60 tonnes of equipment, including generators, inflatable rescue boats, Outboard Motors, and excavators, have also been brought to Sri Lanka, it said, adding that 185 tonnes of Bailey Bridge units were airlifted to restore critical connectivity along with 44 engineers.
Two columns of the National Disaster Response Force, comprising 80 experts and K9 units with specially trained dogs, assisted with immediate rescue and relief efforts in Sri Lanka.
Besides the field hospital in Mahiyanganaya, medical centres have also been set up in the badly hit Ja-Ela region and in Negombo. INS Vikrant, INS Udaygiri, and INS Sukanya provided immediate rescue and relief assistance to Sri Lanka.
Apart from the two Chetak helicopters deployed from INS Vikrant, two heavy-lift, MI-17 helicopters of the Indian Air Force are actively involved in evacuations and airlifting relief material, the release said.
At the request of the Sri Lankan Disaster Management Centre, a virtual meeting was organised between DMC and the Indian Space Research Organisation (ISRO)'s National Remote Sensing Centre on Saturday.
Since the onset of the disaster, ISRO has been providing maps to assist DMC in its rescue efforts, the release said.
