NeoCov coronavirus found in bats may pose threat to humans in future, Chinese scientists caution
Beijing, Jan 28: A type of coronavirus, NeoCov, that spreads among bats in South Africa may pose a threat to humans in future if it mutates further, according to a study by Chinese researchers.
The yet-to-be peer-reviewed study recently posted on the preprint repository BioRxiv, shows that NeoCov is closely related to the Middle East respiratory syndrome (MERS), a viral disease first identified in Saudi Arabia in 2012.
Coronaviruses are a large family of viruses that can cause diseases ranging from the common cold to Severe Acute Respiratory Syndrome (SARS).
Researchers from Chinese Academy of Sciences and Wuhan University noted that NeoCov is found in a population of bats in South Africa and to date spreads exclusively among these animals.
In its current form, NeoCov does not infect humans but further mutations may make it potentially harmful, the researchers noted.
"In this study, we unexpectedly found that NeoCoV and its close relative, PDF-2180-CoV, can efficiently use some types of bat Angiotensin-converting enzyme 2 (ACE2) and, less favourably, human ACE2 for entry," the authors of the study noted.
ACE2 is a receptor protein on cells that provides the entry point for the coronavirus to hook into and infect a wide range of cells.
"Our study demonstrates the first case of ACE2 usage in MERS-related viruses, shedding light on a potential bio-safety threat of the human emergence of an ACE2 using "MERS-CoV-2" with both high fatality and transmission rate," they said.
The researchers further noted that infection with NeoCov could not be cross-neutralised by antibodies targeting SARS-CoV-2 or MERS-CoV.
"Considering the extensive mutations in the RBD regions of the SARS-CoV-2 variants, especially the heavily mutated Omicron variant, these viruses may hold a latent potential to infect humans through further adaptation," the authors of the study added.
A receptor-binding domain (RBD) is a key part of a virus that allows it to dock to body receptors to gain entry into cells and lead to infection.
Let the Truth be known. If you read VB and like VB, please be a VB Supporter and Help us deliver the Truth to one and all.
Deputy CM Shivakumar announces property ownership drive in Bengaluru
Bengaluru (PTI): Karnataka Deputy Chief Minister D K Shivakumar announced a major property ownership drive here aimed at correcting and regularising property records, saying the government had already rectified 23 lakh Khatas and enabled citizens to download their documents online.
Shivakumar, who also holds the Bengaluru Development portfolio, said the state government had begun converting B-Khatas into A-Khatas and would organise special Khata camps every Saturday across corporation limits from May 16 to help citizens secure their property documents.
A Khata is a legal document in Bengaluru certifying that a property complies with all local by-laws, regulations and has paid property taxes to the civic body.
“We have already corrected 23 lakh khatas and provided an opportunity for people to download them,” he said.
Shivakumar explained that the major campaign has been undertaken in Bengaluru to streamline property documentation.
The Deputy Chief Minister said between five and 10 centres would be set up in every corporation area as part of the “Khata Andolana” programme and urged citizens to participate in large numbers.
“I appeal to people to safeguard their property documents. We have created an opportunity for all citizens,” he said.
Calling it a "people-centric" initiative, Shivakumar said the government was working to ensure citizens received proper ownership documentation for their properties.
Shivakumar further claimed that the initiative had drawn national attention and said the Union government had recognised Karnataka with an award for the programme.
“Your Khata is your right. Obtain your Khata and protect yourself from fraud,” he said, while urging people to take advantage of the scheme.
