WHO designates new Covid strain as Variant of Concern, names it 'Omicron'
United Nations/Geneva, Nov 27: The new COVID-19 variant B.1.1.529, first detected from South Africa this week, was on Friday designated as a Variant of Concern by the World Health Organisation, which named it Omicron.
A variant of concern is the WHO's top category of worrying Covid variants.
The WHO said the Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE), an independent group of experts that periodically monitors and evaluates the evolution of SARS-CoV-2 and assesses if specific mutations and combinations of mutations alter the behaviour of the virus, convened on Friday to assess the B.1.1.529 variant, first reported to the world health body from South Africa on November 24.
"The new #COVID19 virus variant - Omicron - has a large number of mutations, some of which are concerning. This is why we need to speed up our efforts to deliver on #VaccinEquity ASAP and protect the most vulnerable everywhere," WHO Director-General Tedros Adhanom Ghebreyesus tweeted.
Based on the evidence presented indicative of a detrimental change in COVID-19 epidemiology, the TAG-VE has advised WHO that this variant should be designated as a Variant of Concern, and the WHO has designated B.1.1.529 as a VOC, named Omicron under its Greek-letter system.
"This variant has a large number of mutations, some of which are concerning. Preliminary evidence suggests an increased risk of reinfection with this variant, as compared to other VOCs. The number of cases of this variant appears to be increasing in almost all provinces in South Africa," the WHO said in a press release.
The variant, first reported to WHO from South Africa on Wednesday, has also been identified in Botswana, Belgium, Hong Kong and Israel.
The WHO has countries to enhance surveillance and sequencing efforts to better understand circulating SARS-CoV-2 variants, submit complete genome sequences and associated metadata to a publicly available database.
Countries are also advised that where capacity exists and in coordination with the international community, they should perform field investigations and laboratory assessments to improve understanding of the potential impacts of the VOC on COVID-19 epidemiology, severity, effectiveness of public health and social measures, diagnostic methods, immune responses, antibody neutralisation, or other relevant characteristics.
"The epidemiological situation in South Africa has been characterised by three distinct peaks in reported cases, the latest of which was predominantly the Delta variant. In recent weeks, infections have increased steeply, coinciding with the detection of B.1.1.529 variant, WHO said, adding that the first known confirmed B.1.1.529 infection was from a specimen collected on November 9.
WHO said current SARS-CoV-2 PCR diagnostics continue to detect this variant. Several labs have indicated that for one widely used PCR test, one of the three target genes is not detected (called S gene dropout or S gene target failure) and this test can therefore be used as marker for this variant, pending sequencing confirmation.
Using this approach, this variant has been detected at faster rates than previous surges in infection, suggesting that this variant may have a growth advantage, the global health organisation said.
WHO added that there are a number of studies underway and the TAG-VE will continue to evaluate this variant. WHO will communicate new findings with the member states and to the public as needed.
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Thailand, Cambodia agree to ceasefire talks after Trump steps in, but border clashes persist
Surin (Thailand) (AP): Thailand and Cambodia on Sunday signalled their readiness to negotiate an end to a deadly border dispute following mediation efforts by US President Donald Trump. The fighting, now in its fourth day, has killed at least 33 people and displaced more than 168,000.
Trump posted on Truth Social on Saturday that he spoke to the leaders of Thailand and Cambodia and suggested he would not move forward with trade agreements with either country if the hostilities continued. He later said both sides agreed to meet to negotiate a ceasefire.
Cambodian Prime Minister Hun Manet said Sunday his country agreed to pursue an “immediate and unconditional ceasefire.” He said Trump told him that Thailand had also agreed to halt attacks following Trump's conversation with Acting Thai Prime Minister Phumtham Wechayachai.
“This is positive news for the soldiers and people of both countries,” Hun Manet said in a statement.
He said he tasked his deputy, Foreign Minister Prak Sokhonn, to coordinate next steps with US Secretary of State Marco Rubio and to engage directly with Thailand's foreign minister to implement the ceasefire.
Thailand expressed cautious support. Phumtham thanked Trump and said that Thailand agreed in principle to a ceasefire but stressed the need for “sincere intention” from Cambodia, the Thai Foreign Ministry said. Phumtam called for swift bilateral talks to discuss concrete steps toward a peaceful resolution, it said.
The fighting first flared Thursday after a land mine explosion along the border wounded five Thai soldiers. Both sides blamed each other for starting the clashes. Both countries recalled their ambassadors and Thailand closed its border crossings with Cambodia.
Despite the diplomatic efforts, fighting continued Sunday along parts of the contested border, with both sides refusing to budge and trading blame over renewed shelling and troop movements.
Col Richa Suksowanont, a Thai army deputy spokesperson, said Cambodian forces fired heavy artillery into Surin province, including at civilian homes early Sunday. He said Cambodia also launched rocket attacks targeting the ancient Ta Muen Thom temple claimed by both countries, and other areas in a bid to reclaim territory secured by Thai troops. Thai forces responded with long-range artillery to strike Cambodian artillery and rocket launchers.
Richa said Trump's efforts to mediate was a “separate matter.” The battlefield operations will continue and a ceasefire can only happen if Cambodia formally initiates negotiations, he added.
“Any cessation of hostilities cannot be reached while Cambodia is severely lacking in good faith and repeatedly violating the basic principles of human rights and humanitarian law," Thailand's Foreign Ministry said separately.
Cambodian Defense Ministry spokesperson Lt. Gen. Maly Socheata accused Thai forces of escalating the violence with bombardment of Cambodian territory early Sunday, followed by a "large-scale incursion" involving tanks and ground troops in multiple areas.
“Such actions undermine all efforts toward peaceful resolution and expose Thailand's clear intent to escalate rather than de-escalate the conflict,” she said.
Thailand has reported 20 deaths, mostly civilians, while Cambodia said 13 people have been killed. More than 131,000 people in Thailand have evacuated to safe locations and over 37,000 people fled from three Cambodian provinces. Many border villages are mostly deserted, with many schools and hospitals shut.
Pichayut Surasit, an air-conditioning technician in Thailand, said the sudden outbreak of fighting meant leaving his work in Bangkok to return home to protect his family.
“I didn't have the heart to continue with my work when I heard the news. I wanted to come back as soon as possible but I had to wait until the evening,” he said. Now at a shelter in Surin housing some 6,000 evacuees, Pichayut worries for his wife and twin daughters, hoping the conflict will end soon so they can return to their home in Kap Choeng district, one of the hardest hit by shelling.
Bualee Chanduang, a local vendor who moved to the same shelter Thursday with her family and pet rabbit, is counting on swift negotiations to end the violence. “I pray for God to help that both sides can agree to talk and end this war,” she said.
The U.N. Security Council has called on the Association of Southeast Asian Nations, a regional bloc, to mediate peace between the two members. Human Rights Watch has condemned the reported use of cluster munitions, weapons banned by International law, in populated areas, and urged both governments to protect civilians.
The 800-kilometer (500-mile) frontier between Thailand and Cambodia has been disputed for decades, but past confrontations have been limited and brief. The latest tensions flared in May when a Cambodian soldier was killed in a confrontation that created a diplomatic rift and roiled Thailand's domestic politics.
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