New Delhi, July 19: Love to gorge on beef jerky, salami, hot dogs and other processed meat as part of your evening snacks daily? Beware, these processed meats laced with chemicals such as nitrates, to preserve them from spoilage, may contribute to mania -- an abnormal mood state characterized by hyperactivity, euphoria and insomnia, a study has found.
The findings showed that people hospitalised for an episode of mania had more than three times the odds of having ever eaten nitrate-cured meats than people without a history of a serious psychiatric disorder.
"We looked at a number of different dietary exposures and cured meat really stood out. It wasn't just that people with mania have an abnormal diet," said lead author Robert Yolken, Professor at the Johns Hopkins University in the US.
Nitrates have long been used as preservatives in cured meat products and have been previously linked to some cancers and neurodegenerative diseases, so Yolken suspected they may also explain the link to mood states such as mania.
Further, in experiments on rats, those who received the jerky showed irregular sleeping patterns and hyperactivity similar to that seen in patients with mania -- increased activity during normal sleep times and in new environments.
However, when the animals were fed on nitrate-free meat, they behaved similarly to a control group.
"It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated maniac episodes," explained Seva Khambadkone, doctoral student at the varsity.
"Our results suggest that nitrated cured meat could be one environmental player in mediating mania," Khambadkone added.
Moreover, the animals with nitrate in their diet had different patterns of bacteria living in their intestines than the other rats and had differences in several molecular pathways in the brain that have been previously implicated in bipolar disorder.
"Future work on this association could lead to dietary interventions to help reduce the risk of manic episodes in those who have bipolar disorder or who are otherwise vulnerable to mania," Yolken said.
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New Delhi: Supreme Court judge Justice Ujjal Bhuyan has strongly criticised the practice of demolishing the properties of individuals accused of crimes, equating it to bulldozing the Constitution and undermining the rule of law.
Speaking at the 13th Justice PN Bhagwati International Moot Court Competition on Human Rights at Bharati Vidyapeeth New Law College in Pune, Justice Bhuyan described the trend as "disturbing" and "depressing." He questioned the justification of such actions, often defended as targeting illegal structures, and highlighted their impact on the families of the accused.
"Using a bulldozer to demolish a property is like running a bulldozer over the Constitution. It is a negation of the very concept of the rule of law and, if not checked, would destroy the very edifice of our justice delivery system," he said, as quoted by Bar and Bench.
The practice of ‘bulldozer justice’ gained prominence in Uttar Pradesh under the Yogi Adityanath government in 2017 and has since been adopted in other states. The Supreme Court had previously deemed this approach unacceptable under the rule of law.
Justice Bhuyan emphasised that demolitions impact not just the accused but their families as well. "In that house, his mother stays there, his sister stays there, his wife stays there, his children stay there. What is their fault?" he asked. He further questioned whether it was justifiable to render an accused or even a convicted person homeless through such measures.
On the same day, Maharashtra Chief Minister Devendra Fadnavis, responding to queries about the recent violence in Nagpur, indicated that the government might consider similar measures. "The Maharashtra government has its own style of working… bulldozer will roll when necessary," he said.
Violence erupted in central Nagpur following rumours that a sacred text was burnt during an agitation by a right-wing group demanding the removal of Mughal emperor Aurangzeb’s tomb in Chhatrapati Sambhajinagar district.
Justice Bhuyan, who was appointed to the Supreme Court in 2023 after serving as Chief Justice of the Telangana High Court, reiterated the importance of upholding due process and warned against actions that undermine constitutional principles.